A Correlation Study of Mammography and Pathology in Inflammatory Breast Cancer

目的认识炎性乳癌特异性与非特异性表现，提高炎性乳癌的术前诊断率。方法回顾性分析经手术病理证实的12例炎性乳癌的临床、X线表现、治疗情况及病理类型。结果12例中9例（75％）为典型炎性乳癌，临床有皮肤红肿等炎症表现，X线片内可见肿块，伴或不伴有钙化，皮肤增厚，乳腺密度增高、紊乱，腋下淋巴结肿大。1例为隐匿型，触诊及X线可见肿块，病理可见淋巴管癌栓，但临床无炎症表现。2例不典型，临床有炎症表现，X线片内未见具体肿块，仅表现为乳腺密度增高、紊乱，皮肤增厚，抗炎治疗无效后经手术切除病理证实为炎性乳癌。炎性乳癌的病理分型主要有浸润型导管癌、浸润型小叶癌。均有淋巴管癌栓。结论对于临床有炎症表现，结合X线所见综合分析是炎性乳癌术前诊断的关键。Objective To identify the characteristics and non-characteristicsof inflammatory breast cancer (IBC) and to improve the diagnosis of IBC.Methods A retrospective analysis was made for the clinical,mammography findings,treatment and pathologic diagnosis in 12 women with IBC who were operated.Results The typical IBC were present in 9 of the 12 women (75％),skin thickness and redness were present at physical examination and skin thickening,stromal coarsening and/or diffusely increased breast density,associated with evidence of a primary tumor mass and/or calcifications were evident at mammography.One case was occult IBC:a palpable mass was present and occurrence of dermal lymphatic involvement without inflammatory signs; two case of the 12 women were non-typical IBC,redness and edema were present in clinical examination without a palpable/visual mass,anti-inflammatory treatment were no null and voil.The pathologic diagnosis of IBC is based on the present of tumor emboil in dermal lymphatic vessels.Conclusion To analysis the clinic characteristics and mammographic findings is the key to diagnosis of IBC.中国科学引文数据库(CSCD)0165-661