Hyperuricaemia and blood pressure, and blood lipid and glucose

目的 探讨企业职工高尿酸血症(HUA)与血压、血脂、血糖的相关性,为企业进行健康管理提供依据.方法 以中国石油长庆油田公司各下属企业为抽样单位,整群随机抽取2个单位,每个单位中所有的HUA者作为HUA组,共720人;同时在尿酸水平正常者中随机选取620人为正常组.通过Logistic回归分析HUA与年龄、性别、血压、血脂、血糖的关系.结果 HUA合并高血压、高血脂、空腹血糖受损任意一项、两项、三项的比例均远高于正常组(OR值分别为:4.036,2.562,4.174).多因素Logistic回归发现:男性、收缩压、总胆固醇、三酰甘油、低密度脂蛋白胆固醇是HUA的危险因素(OR值分别为7.736,2.309,1.721,2.761,1.411);高密度脂蛋白胆固醇为HUA的保护因素(OR值为0.211).结论 HUA存在性别差异,且与血压、血脂密切相关.企业对职工的健康管理应充分考虑多危险因素的综合作用,全面的进行健康教育及干预.Objective To explore the correlation between hyperuricaemia and blood pressure, and blood lipid and glucose. Methods By using simple cluster sampling, 2 branch units from PetroChina Changqing Oilfield Company were selected, and all the 720 subjects with hyperuricaemia (HUA) were assigned to the HUA group; another 620 participants with normal uric acid (UA) level into the normal group. The correlation between blood uric acid and blood pressure,and blood lipid and glucose was assessed by Logistic regression. Results The odds ratio (OR) of those who had 1,2 or 3 abnormal status of hypertension,hyperlipidemia and impaired fasting glucose in the HUA group were much higher than the normal group (OR values were 4. 036,2. 562, and 4. 174, respectively). Logistic regression showed that male, systolic blood pressure ( SBP), GLU, total cholesterol ( TC), triglyceride ( TG), low-density lipoprotein cholesterol (LDL-C) were risk factors of H UA ( OR values were 7. 736,2. 309,1.721,2. 761 and 1. 411,respectively) ,while high-density lipoprotein cholesterol (HDL-C, OR = 0. 211 ) was a protective factor of HUA. Conclusions Gender,blood pressure and blood lipid may have correlation with blood UA. Multiple risk factors should be considered to improve the effectiveness of health education and health promotion.中国科技核心期刊(ISTIC)0287-900