Studies on the chemical constituents in herbs of ethanolic extract from herbs of Dicliptera chinensis

目的:对狗肝菜Dicliptera chinensis全草的化学成分进行研究.方法:采用硅胶柱色谱和制备性薄层色谱及反相HPLC进行分离、纯化,UV,NMR和MS等方法进行结构鉴定.结果:从狗肝菜乙醇提取物的醋酸乙酯萃取部分得到7个化合物,分别鉴定为环八硫(1),开环异落叶松脂醇二甲醚二乙酸酯(2),5-甲氧基-4,4′-二氧甲基开环落叶松脂醇二乙酸酯(3),羟基华远志内酯甲醚(4),黑麦草内酯(5),β-谷甾醇葡萄糖苷(6),豆甾醇葡萄糖苷(7).结论:除化合物6外,其他化合物皆为首次从该属植物中发现.To study the chemical constituents of ethanolic extract from herbs of Dicliptera chinensis.The compounds were separated by silica gel column chromatography, preparation TLC and reverse phase HPLC, their structures were identified by the spectroscopic methods of UV, NMR and MS.Seven compounds were isolated from ethyl acetate extract. Their structure were identified as octasulphur (1), secoisolariciresinol dimethyl ether diacetate (2), 5-methoxy-4, 4'-di-O-methyl secolariciresinol (3), chinensinaphthol methyl ester (4), loliolide (5), beta-sitosterol 3-O-beta-D-glucopyranoside (6) and stigmasterol 3-O-beta-D-glucopyranoside (7).All the compounds except 6 were obtained from the plants of Dicliptera for the first time.PubMed中文核心期刊要目总览(PKU)中国科学引文数据库(CSCD)012985-9873