Point-of-care applications rely on biomedical sensors to enable rapid detection with high sensitivity and selectivity. Despite advances in sensor development, there are challenges in cancer diagnostics. Detection of biomarkers, cell receptors, circulating tumor cells, gene identification, and fluorescent tagging are time-consuming due to the sample preparation and response time involved. Here, we present a novel approach to target the enhanced metabolism in breast cancers for rapid detection using fluorescent imaging. Fluorescent analogs of fructose target the fructose-specific transporter GLUT5 in breast cancers and have limited to no response from normal cells. These analogs demonstrate a marked difference in adenocarcinoma and premaligna...
A major goal of biomedical research has been the early and quantitative identification of patients w...
Abstract Background Epithelial ovarian cancer (OC) is the most lethal gynecological malignancy and p...
When monitoring response to cancer therapy, it is important to differentiate changes in glucose trac...
Point-of-care applications rely on biomedical sensors to enable rapid detection with high sensitivit...
Abstract Alterations in nutritional uptake and metabolism is a crucial hallmark of cancer. As cancer...
As of January 2018, there are 3.1 million women diagnosed of breast cancer. The 5-year survival rate...
F18 2-Fluoro 2-deoxyglucose (FDG) has been the gold standard in positron emission tomography (PET) o...
F18 2-Fluoro 2-deoxyglucose (FDG) has been the gold standard in positron emission tomography (PET) o...
Fructose, a simple sugar abundantly present in fruits, vegetables, and sweetened beverages, plays a ...
<p>Functional imaging gives clinicians the ability to monitor breast cancer progression and response...
The direct relationship between facilitative glucose transporters (GLUTs) and metabolic diseases ope...
The mesenchymal state in cancer is usually associated with poor prognosis due to the metastatic pred...
Because the transition from oxidative phosphorylation to anaerobic glycolytic metabolism is a hallma...
Abstract We previously reported that tumor mitochondrial redox state and its heterogen...
The glucose metabolism rate in cancer cells is a crucial piece of information for the cancer aggress...
A major goal of biomedical research has been the early and quantitative identification of patients w...
Abstract Background Epithelial ovarian cancer (OC) is the most lethal gynecological malignancy and p...
When monitoring response to cancer therapy, it is important to differentiate changes in glucose trac...
Point-of-care applications rely on biomedical sensors to enable rapid detection with high sensitivit...
Abstract Alterations in nutritional uptake and metabolism is a crucial hallmark of cancer. As cancer...
As of January 2018, there are 3.1 million women diagnosed of breast cancer. The 5-year survival rate...
F18 2-Fluoro 2-deoxyglucose (FDG) has been the gold standard in positron emission tomography (PET) o...
F18 2-Fluoro 2-deoxyglucose (FDG) has been the gold standard in positron emission tomography (PET) o...
Fructose, a simple sugar abundantly present in fruits, vegetables, and sweetened beverages, plays a ...
<p>Functional imaging gives clinicians the ability to monitor breast cancer progression and response...
The direct relationship between facilitative glucose transporters (GLUTs) and metabolic diseases ope...
The mesenchymal state in cancer is usually associated with poor prognosis due to the metastatic pred...
Because the transition from oxidative phosphorylation to anaerobic glycolytic metabolism is a hallma...
Abstract We previously reported that tumor mitochondrial redox state and its heterogen...
The glucose metabolism rate in cancer cells is a crucial piece of information for the cancer aggress...
A major goal of biomedical research has been the early and quantitative identification of patients w...
Abstract Background Epithelial ovarian cancer (OC) is the most lethal gynecological malignancy and p...
When monitoring response to cancer therapy, it is important to differentiate changes in glucose trac...