International audienceCD95 (also known as Fas) is a member of the tumor necrosis factor receptor (TNFR) superfamily. Its cognate ligand, CD95L, is implicated in immune homeostasis and immune surveillance. Mutations in this receptor are associated with a loss of apoptotic signaling and have been detected in an autoimmune disorder called autoimmune lymphoproliferative syndrome (ALPS) type Ia, which shares some clinical features with systemic lupus erythematosus (SLE). In addition, deletions and mutations of CD95 have been described in many cancers, which led researchers to initially classify this receptor as a tumor suppressor. More recent data demonstrate that CD95 engagement evokes nonapoptotic signals that promote inflammation and carcinog...
International audienceCD95L (also known as FasL or CD178) is a member of the tumor necrosis family (...
AbstractThe CD95/Fas/Apo-1 ligand is expressed on activated lymphocytes, NK cells, platelets, certai...
International audienceAlthough CD95L (also known as FasL) is still predominantly considered as a dea...
International audienceCD95 (also known as Fas) is a member of the tumor necrosis factor receptor (TN...
International audienceApoptosis is a fundamental process that contributes to tissue homeostasis, imm...
International audienceEndothelial cells lining new blood vessels that develop during inflammatory di...
International audienceApoptosis has emerged as a fundamental process important in tissue homeostasis...
International audienceCD95 (also known as Fas) is the prototype of death receptors; however, evidenc...
International audienceCell death plays a pivotal role in the maintenance of tissue homeostasis. Key ...
International audienceAlthough the interaction of CD95L (also known as FasL) with its so-called deat...
Abstract The TNF receptor superfamily member CD95 (Fas, APO-1, TNFRSF6) is known as the prototypic d...
CD95 (Fas/Apo-1) is a broadly expressed death receptor involved in a variety of physiological and pa...
International audienceCD95L (also known as FasL or CD178) is a member of the tumor necrosis family (...
AbstractThe CD95/Fas/Apo-1 ligand is expressed on activated lymphocytes, NK cells, platelets, certai...
International audienceAlthough CD95L (also known as FasL) is still predominantly considered as a dea...
International audienceCD95 (also known as Fas) is a member of the tumor necrosis factor receptor (TN...
International audienceApoptosis is a fundamental process that contributes to tissue homeostasis, imm...
International audienceEndothelial cells lining new blood vessels that develop during inflammatory di...
International audienceApoptosis has emerged as a fundamental process important in tissue homeostasis...
International audienceCD95 (also known as Fas) is the prototype of death receptors; however, evidenc...
International audienceCell death plays a pivotal role in the maintenance of tissue homeostasis. Key ...
International audienceAlthough the interaction of CD95L (also known as FasL) with its so-called deat...
Abstract The TNF receptor superfamily member CD95 (Fas, APO-1, TNFRSF6) is known as the prototypic d...
CD95 (Fas/Apo-1) is a broadly expressed death receptor involved in a variety of physiological and pa...
International audienceCD95L (also known as FasL or CD178) is a member of the tumor necrosis family (...
AbstractThe CD95/Fas/Apo-1 ligand is expressed on activated lymphocytes, NK cells, platelets, certai...
International audienceAlthough CD95L (also known as FasL) is still predominantly considered as a dea...