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DLC1 (deleted in liver cancer 1)

Ko, FCF
Ng, IOL
Yam, JWP

Publication date

January 2011

DOI

10.4267/2042/44958

Publisher

INIST-CNRS

Journal

Atlas of Genetics and Cytogenetics in Oncology and Haematology

Abstract

Review on DLC1 (deleted in liver cancer 1), with data on DNA, on the protein encoded, and where the gene is implicated

Extracted data

Related items

Attenuation of growth suppression activity of deleted in liver cancer 1 (DLC1) tumor suppressor by Akt phoshorylation

Chan, LK
Ko, FCF
Yam, JWP
Ng, IOL

January 2009

Deleted in liver cancer 1 (DLC1) was identified as a putative tumor suppressor in hepatocellular car...

DLC1 is a chromosome 8p tumor suppressor whose loss promotes hepatocellular carcinoma

Xue, W.
Krasnitz, A.
Lucito, R.
Sordella, R.
Van Aelst, L.
Cordon-Cardo, C.
Singer, S.
Kuehnel, F.
Wigler, M. H.
Powers, S.
Zender, L.
Lowe, S. W.

June 2008

Deletions on chromosome 8p are common in human tumors, suggesting that one or more tumor suppressor ...

Tumor suppressor deleted in liver cancer-1 (DLC-1) gene triggers apoptosis in NPC cells by perturbing mitochondria (MI)

Huang, WL
Zhang, XN
Huang, PC
Wong, CM

January 2008

DLC-1 is a bona fide tumor suppressor gene (TSG) mapped to chromosome 8p22-p21, a region frequently ...

Deleted in liver cancer 1 isoforms are distinctly expressed in human tissues, functionally different and under differential transcriptional regulation in hepatocellular carcinoma

Chan, LK
Poon, RTP
Wong, CM
Yam, JWP
Ng, IOL
Yeung, YS
Ko, FCF

January 2010

Background: Deleted in liver cancer (DLC) is a family of tumour suppressors that plays a critical ro...

Genetic and Epigenetic Alterations of DLC-1 Gene in Hepatocellular Carcinoma

Lee, JMF
Ching, YP
Jin, DY
Ng, IOL
Wong, CM

January 2003

Hepatocellular carcinoma (HCC) is one of the most common fatal cancers in the world. However, the un...

DLC-1 is deleted in primary hepatocellular carcinoma and exerts inhibitory effects on the proliferation of hepatoma cell lines with deleted DLC-1

Lee, TKW
Cao, L
Ng, IOL
Liang, ZD

January 2000

We investigated the expression and deletion of DLC-1 (frequently deleted in liver cancer gene), firs...

The deleted in liver cancer 1 (DLC-1) gene encodes a GTPase activating protein that acts as a negati...

A novel isoform of the 8p22 tumor suppressor gene DLC1 suppresses tumor growth and is frequently silenced in multiple common tumors

Ng, KM
Tao, Q
Low, JSW
Chan, ATC
Srivastava, G
Hsieh, WS
Shamay, M
Ambinder, RF
Woo, WL
Shu, XS
Popescu, NC
Goh, HK

January 2011

The critical 8p22 tumor suppressor deleted in liver cancer 1 (DLC1) is frequently inactivated by abe...

Deleted in Liver Cancer 2 (DLC2) protein expression in hepatocellular carcinoma

Dominika Wolosz
Agnieszka Walczak
Grzegorz Szparecki
Michal Dwojak
Magdalena Winiarska
Ewa Wolinska
Barbara Gornicka

February 2019

Deleted in Liver Cancer (DLC) proteins belong to the family of RhoGAPs and are believed to operate a...

DLG1 (discs, large homolog 1 (Drosophila))

Massimi, P
Banks, L

January 2010

Review on DLG1 (discs, large homolog 1 (Drosophila)), with data on DNA, on the protein encoded, and ...

DLC3 expression in hepatocellular carcinoma

Wolosz, D.
Szparecki, G.
Wolinska, E.
Gornicka, B.

January 2015

Introduction and objective. Deleted in Liver Cancer (DLC) proteins belong to the family of RhoGAPs a...

Deleted in Liver Cancer 1 (DLC1) is a negative regulator of metastasis and deregulated by kinase phosphorylation in hepatocellular carcinoma

Yam, JWP
Ko, FCF
Chan, LK
Tung, KK
Ng, IOL

January 2010

Session - Cellular and Molecular Biology: no. 5003Deleted in liver cancer 1 (DLC1), which encodes a ...

Restoration of DLC1 Gene Inhibits Proliferation and Migration of Human Colon Cancer HT29 Cells

September 2016

Abstract. DLC1 (deleted in liver cancer-1) is a new candidate tumor suppressor gene, which is inacti...

DLC-1 suppresses non-small cell lung cancer growth and invasion by RhoGAP-dependent and independent mechanisms

Healy, Kevin D.
Hodgson, Louis
Kim, Tai-Young
Shutes, Adam
Maddileti, Savitri
Juliano, Rudolph L.
Hahn, Klaus M.
Harden, T. Kendall
Bang, Yung-Jue
Der, Channing J.

January 2008

Expression of the tumor suppressor deleted in liver cancer-1 (DLC-1) is lost in non-small cell lung ...

Mitochondrial targeting of growth suppressor protein DLC2 through the START domain

Ng, David Chi-Heng
Chan, Shing-Fai
Kok, Kin Hang
Yam, Judy Wai Ping
Ching, Yick-Pang
Ng, Irene Oi-lin
Jin, Dong-Yan

January 2006

AbstractDeleted in liver cancer 2 (DLC2) is a candidate tumor suppressor frequently found to be dele...

Attenuation of growth suppression activity of deleted in liver cancer 1 (DLC1) tumor suppressor by Akt phoshorylation

Chan, LK
Ko, FCF
Yam, JWP
Ng, IOL

January 2009

Deleted in liver cancer 1 (DLC1) was identified as a putative tumor suppressor in hepatocellular car...

DLC1 is a chromosome 8p tumor suppressor whose loss promotes hepatocellular carcinoma

Xue, W.
Krasnitz, A.
Lucito, R.
Sordella, R.
Van Aelst, L.
Cordon-Cardo, C.
Singer, S.
Kuehnel, F.
Wigler, M. H.
Powers, S.
Zender, L.
Lowe, S. W.

June 2008

Deletions on chromosome 8p are common in human tumors, suggesting that one or more tumor suppressor ...

Tumor suppressor deleted in liver cancer-1 (DLC-1) gene triggers apoptosis in NPC cells by perturbing mitochondria (MI)

Huang, WL
Zhang, XN
Huang, PC
Wong, CM

January 2008

DLC-1 is a bona fide tumor suppressor gene (TSG) mapped to chromosome 8p22-p21, a region frequently ...

Deleted in liver cancer 1 isoforms are distinctly expressed in human tissues, functionally different and under differential transcriptional regulation in hepatocellular carcinoma

Chan, LK
Poon, RTP
Wong, CM
Yam, JWP
Ng, IOL
Yeung, YS
Ko, FCF

January 2010

Background: Deleted in liver cancer (DLC) is a family of tumour suppressors that plays a critical ro...

Genetic and Epigenetic Alterations of DLC-1 Gene in Hepatocellular Carcinoma

Lee, JMF
Ching, YP
Jin, DY
Ng, IOL
Wong, CM

January 2003

Hepatocellular carcinoma (HCC) is one of the most common fatal cancers in the world. However, the un...

DLC-1 is deleted in primary hepatocellular carcinoma and exerts inhibitory effects on the proliferation of hepatoma cell lines with deleted DLC-1

Lee, TKW
Cao, L
Ng, IOL
Liang, ZD

January 2000

We investigated the expression and deletion of DLC-1 (frequently deleted in liver cancer gene), firs...

The deleted in liver cancer 1 (DLC-1) gene encodes a GTPase activating protein that acts as a negati...

A novel isoform of the 8p22 tumor suppressor gene DLC1 suppresses tumor growth and is frequently silenced in multiple common tumors

Ng, KM
Tao, Q
Low, JSW
Chan, ATC
Srivastava, G
Hsieh, WS
Shamay, M
Ambinder, RF
Woo, WL
Shu, XS
Popescu, NC
Goh, HK

January 2011

The critical 8p22 tumor suppressor deleted in liver cancer 1 (DLC1) is frequently inactivated by abe...

Deleted in Liver Cancer 2 (DLC2) protein expression in hepatocellular carcinoma

Dominika Wolosz
Agnieszka Walczak
Grzegorz Szparecki
Michal Dwojak
Magdalena Winiarska
Ewa Wolinska
Barbara Gornicka

February 2019

Deleted in Liver Cancer (DLC) proteins belong to the family of RhoGAPs and are believed to operate a...

DLG1 (discs, large homolog 1 (Drosophila))

Massimi, P
Banks, L

January 2010

Review on DLG1 (discs, large homolog 1 (Drosophila)), with data on DNA, on the protein encoded, and ...

DLC3 expression in hepatocellular carcinoma

Wolosz, D.
Szparecki, G.
Wolinska, E.
Gornicka, B.

January 2015

Introduction and objective. Deleted in Liver Cancer (DLC) proteins belong to the family of RhoGAPs a...

Deleted in Liver Cancer 1 (DLC1) is a negative regulator of metastasis and deregulated by kinase phosphorylation in hepatocellular carcinoma

Yam, JWP
Ko, FCF
Chan, LK
Tung, KK
Ng, IOL

January 2010

Session - Cellular and Molecular Biology: no. 5003Deleted in liver cancer 1 (DLC1), which encodes a ...

Restoration of DLC1 Gene Inhibits Proliferation and Migration of Human Colon Cancer HT29 Cells

September 2016

Abstract. DLC1 (deleted in liver cancer-1) is a new candidate tumor suppressor gene, which is inacti...

DLC-1 suppresses non-small cell lung cancer growth and invasion by RhoGAP-dependent and independent mechanisms

Healy, Kevin D.
Hodgson, Louis
Kim, Tai-Young
Shutes, Adam
Maddileti, Savitri
Juliano, Rudolph L.
Hahn, Klaus M.
Harden, T. Kendall
Bang, Yung-Jue
Der, Channing J.

January 2008

Expression of the tumor suppressor deleted in liver cancer-1 (DLC-1) is lost in non-small cell lung ...

Mitochondrial targeting of growth suppressor protein DLC2 through the START domain

Ng, David Chi-Heng
Chan, Shing-Fai
Kok, Kin Hang
Yam, Judy Wai Ping
Ching, Yick-Pang
Ng, Irene Oi-lin
Jin, Dong-Yan

January 2006

AbstractDeleted in liver cancer 2 (DLC2) is a candidate tumor suppressor frequently found to be dele...

Attenuation of growth suppression activity of deleted in liver cancer 1 (DLC1) tumor suppressor by Akt phoshorylation

Chan, LK
Ko, FCF
Yam, JWP
Ng, IOL

January 2009

Deleted in liver cancer 1 (DLC1) was identified as a putative tumor suppressor in hepatocellular car...

DLC1 is a chromosome 8p tumor suppressor whose loss promotes hepatocellular carcinoma

Xue, W.
Krasnitz, A.
Lucito, R.
Sordella, R.
Van Aelst, L.
Cordon-Cardo, C.
Singer, S.
Kuehnel, F.
Wigler, M. H.
Powers, S.
Zender, L.
Lowe, S. W.

June 2008

Deletions on chromosome 8p are common in human tumors, suggesting that one or more tumor suppressor ...

Tumor suppressor deleted in liver cancer-1 (DLC-1) gene triggers apoptosis in NPC cells by perturbing mitochondria (MI)

Huang, WL
Zhang, XN
Huang, PC
Wong, CM

January 2008

DLC-1 is a bona fide tumor suppressor gene (TSG) mapped to chromosome 8p22-p21, a region frequently ...