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PTCH1 (patched homolog 1 (Drosophila))

Huret, JL

Publication date

January 1999

DOI

10.4267/2042/37502

Publisher

INIST-CNRS

Journal

Atlas of Genetics and Cytogenetics in Oncology and Haematology

Abstract

Review on PTCH1 (patched homolog 1 (Drosophila)), with data on DNA, on the protein encoded, and where the gene is implicated

Extracted data

Related items

Functional analysis in Drosophila indicates that the NBCCS/PTCH1 mutation G509V results in activation of smoothened through a dominant-negative mechanism

Hime, G. R.
Lada, H.
Fietz, M. J.
Gillies, S.
Passmore, A.
Wicking, C. A.
Wainwright, B. J.

April 2004

Mutations in the human homolog of the patched gene are associated with the developmental (and cancer...

NUMB (numb homolog (Drosophila))

Confalonieri, S
Pece, S
Di, Fiore PP

January 2011

Review on NUMB (numb homolog (Drosophila)), with data on DNA, on the protein encoded, and where the ...

Distinct Consequences of Sterol Sensor Mutations in Drosophila and Mouse patched Homologs

Johnson, Ronald L
Zhou, Lei
Bailey, Evans C

February 2002

AbstractThe membrane protein Patched (Ptc) is a critical regulator of Hedgehog signaling. Ptc is amo...

PLK1 (polo-like kinase 1 (Drosophila))

Erson, AE
Petty, EM

January 2005

Review on PLK1 (polo-like kinase 1 (Drosophila)), with data on DNA, on the protein encoded, and wher...

Allelic Loss at Drosophila Patched Gene Is Highly Prevalent in Basal and Squamous Cell Carcinomas of the Skin

Danaee, Hadi
Karagas, Margaret R.
Kelsey, Karl T.
Perry, Ann E.
Nelson, Heather H

May 2006

The human homolog of the Drosophila Patched gene (PTCH), located at chromosome 9q22.3, is frequently...

NOTCH1 (Notch homolog 1, translocation-associated (Drosophila))

Cayo, M
Greenblatt, DY
Kunnimalaiyaan, M
Chen, H

January 2008

Review on NOTCH1 (Notch homolog 1, translocation-associated (Drosophila)), with data on DNA, on the ...

Spectrum of PTCH1 Mutations in French Patients with Gorlin Syndrome

Boutet, Nathalie
Bignon, Yves-Jean
Drouin-Garraud, Valérie
Sarda, Pierre
Longy, Michel
Lacombe, Didier
Gorry, Philippe

September 2003

Gorlin syndrome or nevoid basal cell carcinoma syndrome is an autosomal dominant disease characteriz...

Mutations of the Human Homolog of Drosophila patched in the Nevoid Basal Cell Carcinoma Syndrome

Hahn, Heidi
Wicking, Carol
Zaphiropoulos, Peter G
Gailani, Mae R
Shanley, Susan
Chidambaram, Abirami
Vorechovsky, Igor
Holmberg, Erika
Unden, Anne Birgitte
Gillies, Susan
Negus, Kylie
Smyth, Ian
Pressman, Carolyn
Leffell, David J
Gerrard, Bernard
Goldstein, Alisa M
Dean, Michael
Toftgard, Rune
Chenevix-Trench, Georgia
Wainwright, Brandon
Bale, Allen E

June 1996

AbstractThe nevoid basal cell carcinoma syndrome (NBCCS) is an autosomal dominant disorder character...

Molecular complexities of patched signaling in cancer development

Rahnama, Fahimeh

June 2004

Basal Cell Cancer (BCC) is the most common cancer in the Western world. Although BCCs hardly ever me...

Identification of Mutations in the Human PATCHED Gene in Sporadic Basal Cell Carcinomas and in Patients with the Basal Cell Nevus Syndrome

Aszterbaum, Michelle
Rothman, Alana
Fisher, Monte
Xie, Jingwu
Bonifas, Jeannette M.
Zhang, Xioli
Epstein, Ervin H.
Johnson, Ronald L.
Scott, Mathew P.

June 1998

Mutations in PATCHED (PTC), the human homolog of the Drosophila patched gene, have been identified i...

PTEN (phosphatase and tensin homolog deleted on chromosome ten)

Longy, M

January 1999

Review on PTEN (phosphatase and tensin homolog deleted on chromosome ten), with data on DNA, on the ...

LATS1 (LATS, large tumor suppressor, homolog 1 (Drosophila))

Visser, S
Yang, X

January 2010

Review on LATS1 (LATS, large tumor suppressor, homolog 1 (Drosophila)), with data on DNA, on the pro...

DVL1 (dishevelled, dsh homolog 1 (Drosophila))

Lee, HJ
Zheng, JJ

January 2011

Review on DVL1 (dishevelled, dsh homolog 1 (Drosophila)), with data on DNA, on the protein encoded, ...

Studies on basal cell carcinoma with emphasis on the role of the human homologue of the Drosophila patched gene

Undén, Anne Birgitte

December 1997

Basal cell cancer (BCC) is the most common cancer in the Western world. AlthoughBCCs hardly ever met...

PTCH germline mutations in Chinese nevoid basal cell carcinoma syndrome patients

Li, T-J
Yuan, J-W
Gu, X-M
Sun, L-S
Zhao, H-S

January 2008

OBJECTIVES: PTCH, the human homologue of the Drosophila segment polarity gene, patched, has been ide...

Functional analysis in Drosophila indicates that the NBCCS/PTCH1 mutation G509V results in activation of smoothened through a dominant-negative mechanism

Hime, G. R.
Lada, H.
Fietz, M. J.
Gillies, S.
Passmore, A.
Wicking, C. A.
Wainwright, B. J.

April 2004

Mutations in the human homolog of the patched gene are associated with the developmental (and cancer...

NUMB (numb homolog (Drosophila))

Confalonieri, S
Pece, S
Di, Fiore PP

January 2011

Review on NUMB (numb homolog (Drosophila)), with data on DNA, on the protein encoded, and where the ...

Distinct Consequences of Sterol Sensor Mutations in Drosophila and Mouse patched Homologs

Johnson, Ronald L
Zhou, Lei
Bailey, Evans C

February 2002

AbstractThe membrane protein Patched (Ptc) is a critical regulator of Hedgehog signaling. Ptc is amo...

PLK1 (polo-like kinase 1 (Drosophila))

Erson, AE
Petty, EM

January 2005

Review on PLK1 (polo-like kinase 1 (Drosophila)), with data on DNA, on the protein encoded, and wher...

Allelic Loss at Drosophila Patched Gene Is Highly Prevalent in Basal and Squamous Cell Carcinomas of the Skin

Danaee, Hadi
Karagas, Margaret R.
Kelsey, Karl T.
Perry, Ann E.
Nelson, Heather H

May 2006

The human homolog of the Drosophila Patched gene (PTCH), located at chromosome 9q22.3, is frequently...

NOTCH1 (Notch homolog 1, translocation-associated (Drosophila))

Cayo, M
Greenblatt, DY
Kunnimalaiyaan, M
Chen, H

January 2008

Review on NOTCH1 (Notch homolog 1, translocation-associated (Drosophila)), with data on DNA, on the ...

Spectrum of PTCH1 Mutations in French Patients with Gorlin Syndrome

Boutet, Nathalie
Bignon, Yves-Jean
Drouin-Garraud, Valérie
Sarda, Pierre
Longy, Michel
Lacombe, Didier
Gorry, Philippe

September 2003

Gorlin syndrome or nevoid basal cell carcinoma syndrome is an autosomal dominant disease characteriz...

Mutations of the Human Homolog of Drosophila patched in the Nevoid Basal Cell Carcinoma Syndrome

Hahn, Heidi
Wicking, Carol
Zaphiropoulos, Peter G
Gailani, Mae R
Shanley, Susan
Chidambaram, Abirami
Vorechovsky, Igor
Holmberg, Erika
Unden, Anne Birgitte
Gillies, Susan
Negus, Kylie
Smyth, Ian
Pressman, Carolyn
Leffell, David J
Gerrard, Bernard
Goldstein, Alisa M
Dean, Michael
Toftgard, Rune
Chenevix-Trench, Georgia
Wainwright, Brandon
Bale, Allen E

June 1996

AbstractThe nevoid basal cell carcinoma syndrome (NBCCS) is an autosomal dominant disorder character...

Molecular complexities of patched signaling in cancer development

Rahnama, Fahimeh

June 2004

Basal Cell Cancer (BCC) is the most common cancer in the Western world. Although BCCs hardly ever me...

Identification of Mutations in the Human PATCHED Gene in Sporadic Basal Cell Carcinomas and in Patients with the Basal Cell Nevus Syndrome

Aszterbaum, Michelle
Rothman, Alana
Fisher, Monte
Xie, Jingwu
Bonifas, Jeannette M.
Zhang, Xioli
Epstein, Ervin H.
Johnson, Ronald L.
Scott, Mathew P.

June 1998

Mutations in PATCHED (PTC), the human homolog of the Drosophila patched gene, have been identified i...

PTEN (phosphatase and tensin homolog deleted on chromosome ten)

Longy, M

January 1999

Review on PTEN (phosphatase and tensin homolog deleted on chromosome ten), with data on DNA, on the ...

LATS1 (LATS, large tumor suppressor, homolog 1 (Drosophila))

Visser, S
Yang, X

January 2010

Review on LATS1 (LATS, large tumor suppressor, homolog 1 (Drosophila)), with data on DNA, on the pro...

DVL1 (dishevelled, dsh homolog 1 (Drosophila))

Lee, HJ
Zheng, JJ

January 2011

Review on DVL1 (dishevelled, dsh homolog 1 (Drosophila)), with data on DNA, on the protein encoded, ...

Studies on basal cell carcinoma with emphasis on the role of the human homologue of the Drosophila patched gene

Undén, Anne Birgitte

December 1997

Basal cell cancer (BCC) is the most common cancer in the Western world. AlthoughBCCs hardly ever met...

PTCH germline mutations in Chinese nevoid basal cell carcinoma syndrome patients

Li, T-J
Yuan, J-W
Gu, X-M
Sun, L-S
Zhao, H-S

January 2008

OBJECTIVES: PTCH, the human homologue of the Drosophila segment polarity gene, patched, has been ide...

Functional analysis in Drosophila indicates that the NBCCS/PTCH1 mutation G509V results in activation of smoothened through a dominant-negative mechanism

Hime, G. R.
Lada, H.
Fietz, M. J.
Gillies, S.
Passmore, A.
Wicking, C. A.
Wainwright, B. J.

April 2004

Mutations in the human homolog of the patched gene are associated with the developmental (and cancer...

NUMB (numb homolog (Drosophila))

Confalonieri, S
Pece, S
Di, Fiore PP

January 2011

Review on NUMB (numb homolog (Drosophila)), with data on DNA, on the protein encoded, and where the ...

Distinct Consequences of Sterol Sensor Mutations in Drosophila and Mouse patched Homologs

Johnson, Ronald L
Zhou, Lei
Bailey, Evans C

February 2002

AbstractThe membrane protein Patched (Ptc) is a critical regulator of Hedgehog signaling. Ptc is amo...