Congrès sous l’égide de la Société Française de Génie Biologique et Médical (SFGBM).National audienceSingle pixel imaging opened the door to a cheaper camera architecture able to operate in a wide spectral range. We propose a new acquisition strategy for such an optical setup. Our technique obtains an image in the wavelet domain with a progressive non-linear acquisition. With a good spatial resolution, this method based on wavelet's compression can be used in fluorescence imaging to observe biological structures