Detection of chondroitin sulfate proteoglycan 4 (CSPG4) in melanoma

Wang, Yangyang
Sabbatino, Francesco
Wang, Xinhui
Ferrone, Soldano

Open link

Publication date

January 2014

DOI

10.1007/978-1-62703-727-3_28

ISSN

1064-3745

Citation count (estimate)

Abstract

The tumor antigen chondroitin sulfate proteoglycan 4 (CSPG4) appears to be a useful biomarker to identify melanoma cells and an attractive target to apply antibody-based immunotherapy for the treatment of melanoma. Here we described the reverse transcription-polymerase chain reaction (RT-PCR) method and the immunohistochemical (IHC) staining method to detect the expression of CSPG4 in melanoma cells and tissues. Â© Springer Science+Business Media New York 2014