Add to ORKGTumor development is a Darwinian evolutionary process, involving the interplay between cancer subclones and the local immune microenvironment. These complex interactions are highlighted in this issue of Cell by the results from Jiménez-Sánchez et al. of a deep analysis of one patient with advanced serous carcinoma of the ovary
The immune system interacts with developing cancer in ways that can protect the host against hyperpr...
Evolutionary processes play a central role in the development, progression and response to treatment...
SummaryThe complex interactions between tumors and their microenvironment remain to be elucidated. C...
Summary Understanding how a tumour evolves and avoids immune recognition is paramount to improving ...
Cancer is well-recognized as an evolutionary system, as first proposed by Cairns and Nowell more tha...
Cancer development is an evolutionary process. A key selection pressure is exerted by therapy, one o...
The evolutionary dynamics of tumor initiation remain undetermined, and the interplay between neoplas...
High-grade serous ovarian cancer (HGSC) is the most common and lethal histotype of epithelial ovaria...
The development of cancer begins with cells transitioning from their multicellular nature to a state...
Forty years ago, scientists started to describe the genetic cascade of events leading to cancer as s...
Cancer heterogeneity is a result of genetic mutations within the cancer cells. Their proliferation i...
Even if cancer stem cells (CSCs) represent only a small proportion of the tumor mass, they significa...
This review explores the incessant evolutionary interaction and co-development between immune system...
Emerging evidence suggests that cancer branched evolution may affect biomarker validation, clinical ...
Host immunity plays a central and complex role in dictating tumour progression. Solid tumours are co...
The immune system interacts with developing cancer in ways that can protect the host against hyperpr...
Evolutionary processes play a central role in the development, progression and response to treatment...
SummaryThe complex interactions between tumors and their microenvironment remain to be elucidated. C...
Summary Understanding how a tumour evolves and avoids immune recognition is paramount to improving ...
Cancer is well-recognized as an evolutionary system, as first proposed by Cairns and Nowell more tha...
Cancer development is an evolutionary process. A key selection pressure is exerted by therapy, one o...
The evolutionary dynamics of tumor initiation remain undetermined, and the interplay between neoplas...
High-grade serous ovarian cancer (HGSC) is the most common and lethal histotype of epithelial ovaria...
The development of cancer begins with cells transitioning from their multicellular nature to a state...
Forty years ago, scientists started to describe the genetic cascade of events leading to cancer as s...
Cancer heterogeneity is a result of genetic mutations within the cancer cells. Their proliferation i...
Even if cancer stem cells (CSCs) represent only a small proportion of the tumor mass, they significa...
This review explores the incessant evolutionary interaction and co-development between immune system...
Emerging evidence suggests that cancer branched evolution may affect biomarker validation, clinical ...
Host immunity plays a central and complex role in dictating tumour progression. Solid tumours are co...
The immune system interacts with developing cancer in ways that can protect the host against hyperpr...
Evolutionary processes play a central role in the development, progression and response to treatment...
SummaryThe complex interactions between tumors and their microenvironment remain to be elucidated. C...