Traitement des douleurs neuropathiques

Introduction :neuropathic pain is a frequent complication and results from numerous mechanisms, (infectious, post traumatic, metabolic, vascular) or toxic (i.e. medications). It is a complex entity due to its pathophysiology and its clinical features, but remains under diagnosed despite medical awareness. Material and method :we reviewed the recent literature on evaluation and treatment of neuropathic pain with a focus on published guidelines Results :Scales and questionnaires are available (DN 4, LANSS, etc.) but are not superior to anamnesis and a close physical examination. Usual treatments mostly based on empirical experiences are antidepressants, anti epileptics, calcium channels inhibitors, opioids, and cannabinoids. Conclusion :neuropathic pain is a complex and heterogeneous syndrome. Various medications are available but none is specific. The best choice is a drug with few interactions and side effects. Some preventive therapies are promising. We propose a practical guideline based on data from the literature.SCOPUS: ar.j