Add to ORKGThe subject invention concerns compositions and methods for blocking cancer cell growth or proliferation and/or inducing cancer cell death. Compositions of the present invention are peptidomimetics that inhibit STAT function. Peptidomimetics of the invention display selective inhibition of specific STAT isoform homo-dimerization. The peptidomimetic probes of STAT1 function, described herein, provide the means to preferentially inhibit STAT1 over STAT3 through the exploration of the C-terminus
The present invention relates to methods for treating and/or preventing cancer. In parti...
More than 50 new inhibitors of the oncogenic Stat3 protein were identified through a structure-activ...
Methods of enhancing antitumor activity of an immune cell comprising contacting the immune cell with...
The subject invention concerns compositions and methods for blocking cancer cell growth or prolifera...
The subject invention concerns compositions and methods for blocking cancer cell growth or prolifera...
The present invention concerns compounds, compositions containing these compounds, and methods of us...
The identification of constitutively activated STAT (Signal Transducers and Activators of Transcript...
The identification of constitutively activated STAT (Signal Transducers and Activators of Transcript...
The present invention concerns compounds, compositions containing these compounds, and methods of us...
A small-molecule Stat3 dimerization inhibitor, S3I-M2001. is described and the dynamics of intracell...
A small-molecule Stat3 dimerization inhibitor, S3I-M2001, is described and the dynamics of intracell...
Signal Transducer and Activator of Transcription (STAT) proteins have a fundamental role cell signal...
Stat-3 (Signal Transduction and Activator of Transcription) is a member of the Stat family of latent...
Stat-3 (Signal Transduction and Activator of Transcription) is a member of the Stat family of latent...
The present invention relates to compositions comprising statin, and especially to the use of such c...
The present invention relates to methods for treating and/or preventing cancer. In parti...
More than 50 new inhibitors of the oncogenic Stat3 protein were identified through a structure-activ...
Methods of enhancing antitumor activity of an immune cell comprising contacting the immune cell with...
The subject invention concerns compositions and methods for blocking cancer cell growth or prolifera...
The subject invention concerns compositions and methods for blocking cancer cell growth or prolifera...
The present invention concerns compounds, compositions containing these compounds, and methods of us...
The identification of constitutively activated STAT (Signal Transducers and Activators of Transcript...
The identification of constitutively activated STAT (Signal Transducers and Activators of Transcript...
The present invention concerns compounds, compositions containing these compounds, and methods of us...
A small-molecule Stat3 dimerization inhibitor, S3I-M2001. is described and the dynamics of intracell...
A small-molecule Stat3 dimerization inhibitor, S3I-M2001, is described and the dynamics of intracell...
Signal Transducer and Activator of Transcription (STAT) proteins have a fundamental role cell signal...
Stat-3 (Signal Transduction and Activator of Transcription) is a member of the Stat family of latent...
Stat-3 (Signal Transduction and Activator of Transcription) is a member of the Stat family of latent...
The present invention relates to compositions comprising statin, and especially to the use of such c...
The present invention relates to methods for treating and/or preventing cancer. In parti...
More than 50 new inhibitors of the oncogenic Stat3 protein were identified through a structure-activ...
Methods of enhancing antitumor activity of an immune cell comprising contacting the immune cell with...