Simulations of recovery of naive CD4 T-cell numbers following depletion.

<p>Under the assumptions of pure density-dependent regulation of naive T-cell numbers (left panels), or the adaptation model (right panels), we simulated recovery from different levels of naive CD4 T-cell depletion at age 200 d (upper panels) and recovery from 50% depletion at different host ages (lower panels). Simulations were performed using the model parameters estimated from the data in ref. [<a href="http://www.plosbiology.org/article/info:doi/10.1371/journal.pbio.2003949#pbio.2003949.ref008" target="_blank">8</a>].