Intra- and inter-cellular signaling pathways have become promising candidates for cancer therapy, because they are frequently affected by oncogenic aberrations and specific small molecule inhibitors are available. The aim of this thesis is to identify and evaluate signaling pathways that may be targeted by novel therapeutic approaches in children with BCP-ALL
PhD ThesisAcute lymphoblastic leukaemia (ALL) is a clonal disorder of developing lymphocytes and is ...
Background: In spite of leukemia therapy improvements obtained over the last decades, therapy is not...
T-cell acute lymphoblastic leukemia is identified in 10-25% of all newly diagnosed acute lymphoblast...
markdownabstractIntra- and inter-cellular signaling pathways have become promising candidates for ca...
Pediatric acute lymphoblastic leukemia (ALL) is a heterogeneous disease, caused by the malignant tra...
This thesis aims to identify leukemia-specific processes that can be used to target leukemic cells o...
Despite intensive chemotherapy, acute lymphoblastic leukemia (ALL) relapse is still a major cause of...
Acute lymphoblastic leukemia (ALL) is a malignant disease characterized by an uncontrolled prolifera...
The aim of this thesis was to study the role of both leukemic and newly generated normal B-cells in ...
Abstract T-cell acute lymphoblastic leukemia (T-ALL) is an aggressive disease caused by the malig...
T-cell acute lymphoblastic leukemia (T-ALL) represents 10-15% of pediatric acute leukemias. Despite ...
__Abstract__ Despite the improvement in prognosis of childhood acute lymphoblastic leukemia (ALL)...
Currently, the intensive chemotherapy remains the first line treatment for B cell acute lymphoblasti...
B-cell acute lymphoblastic leukemia (B-ALL) is a hematologic malignancy that arises from the clonal ...
Nowadays, thanks to extensive studies and progress in precision medicine, pediatric leukemia has rea...
PhD ThesisAcute lymphoblastic leukaemia (ALL) is a clonal disorder of developing lymphocytes and is ...
Background: In spite of leukemia therapy improvements obtained over the last decades, therapy is not...
T-cell acute lymphoblastic leukemia is identified in 10-25% of all newly diagnosed acute lymphoblast...
markdownabstractIntra- and inter-cellular signaling pathways have become promising candidates for ca...
Pediatric acute lymphoblastic leukemia (ALL) is a heterogeneous disease, caused by the malignant tra...
This thesis aims to identify leukemia-specific processes that can be used to target leukemic cells o...
Despite intensive chemotherapy, acute lymphoblastic leukemia (ALL) relapse is still a major cause of...
Acute lymphoblastic leukemia (ALL) is a malignant disease characterized by an uncontrolled prolifera...
The aim of this thesis was to study the role of both leukemic and newly generated normal B-cells in ...
Abstract T-cell acute lymphoblastic leukemia (T-ALL) is an aggressive disease caused by the malig...
T-cell acute lymphoblastic leukemia (T-ALL) represents 10-15% of pediatric acute leukemias. Despite ...
__Abstract__ Despite the improvement in prognosis of childhood acute lymphoblastic leukemia (ALL)...
Currently, the intensive chemotherapy remains the first line treatment for B cell acute lymphoblasti...
B-cell acute lymphoblastic leukemia (B-ALL) is a hematologic malignancy that arises from the clonal ...
Nowadays, thanks to extensive studies and progress in precision medicine, pediatric leukemia has rea...
PhD ThesisAcute lymphoblastic leukaemia (ALL) is a clonal disorder of developing lymphocytes and is ...
Background: In spite of leukemia therapy improvements obtained over the last decades, therapy is not...
T-cell acute lymphoblastic leukemia is identified in 10-25% of all newly diagnosed acute lymphoblast...