Measurement of liver function using hepatobiliary scintigraphy improves risk assessment in patients undergoing major liver resection
- Cieslak, K.P. (Kasia P.)
- Bennink, R.J. (Roelof)
- Graaf, W. (Wilmar) de
- Lienden, K.P. (Krijn) van
- Besselink, M.G. (Marc)
- Busch, O.R.C. (Olivier)
- Gouma, D.J. (Dirk)
- Gulik, T.M. (Thomas) van
DOIAbstract
Background 99mTc-mebrofenin-hepatobiliary-scintigraphy (HBS) enables measurement of future remnant liver (FRL)-function and was implemented in our preoperative routine after calculation of the cut-off value for prediction of postoperative liver failure (LF). This study evaluates our results since the implementation of HBS. Additionally, CT-volumetric methods of FRL-assessment, standardized liver volumetry and FRL/body-weight ratio (FRL-BWR), were evaluated. Methods 163 patients who underwent major liver resection were included. Insufficient FRL-volume and/or FRL-function <2.7%/min/m2 were indications for portal vein embolization (PVE). Non-PVE patients were compared with a historical cohort (n = 55). Primary endpoints were postoperative LF ...
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