Add to ORKGItem does not contain fulltextIn order to identify genes associated with the metastatic phenotype we have compared the expression pattern of 6800 genes in a metastatic (NMCL-1) versus a non-metastatic (530) human melanoma cell line making use of DNA microarrays. The differentially expressed genes identified are involved in control of transcription, regulation of the cell-cycle, proteolysis, cell adhesion, immune response and signaling. A remarkable feature of the system under investigation is the consistent down-regulation of MHC-related and cell adhesion mediating genes in the metastatic cell line
In spite of intensive and increasingly successful attempts to determine the multiple steps involved ...
In order to identify genes relevant for melanoma development, we carried out cDNA array experiments ...
Gene expression profiling has revolutionized our ability to molecularly classify primary human tumor...
In order to identify genes associated with the metastatic phenotype we have compared the expression ...
Metastasis represents a crucial transition in disease development and progression and has a profound...
BackgroundThe process of malignant transformation, progression and metastasis of melanoma is poorly ...
AbstractThe aims of the study were to identify the differentially expressed genes (DEGs) between pri...
Item does not contain fulltextThe increasing incidence of melanoma and the lack of effective treatme...
Metastasis suppressor genes (MS genes) are genes that play important roles in inhibiting the process...
<p>Genome-wide DNase-Seq identifies (DHS) regulatory elements in the cell culture sample from our st...
We are investigating the molecular basis of melanoma by defining genomic characteristics that correl...
BACKGROUND: We are investigating the molecular basis of melanoma by defining genomic characteristics...
Human metastatic cutaneous melanoma has gained a well deserved reputation for its immune responsiven...
In order to identify genes relevant for melanoma development, we carried out cDNA array experiments ...
Abstract Human metastatic cutaneous melanoma has gained a well deserved reputation for its immune re...
In spite of intensive and increasingly successful attempts to determine the multiple steps involved ...
In order to identify genes relevant for melanoma development, we carried out cDNA array experiments ...
Gene expression profiling has revolutionized our ability to molecularly classify primary human tumor...
In order to identify genes associated with the metastatic phenotype we have compared the expression ...
Metastasis represents a crucial transition in disease development and progression and has a profound...
BackgroundThe process of malignant transformation, progression and metastasis of melanoma is poorly ...
AbstractThe aims of the study were to identify the differentially expressed genes (DEGs) between pri...
Item does not contain fulltextThe increasing incidence of melanoma and the lack of effective treatme...
Metastasis suppressor genes (MS genes) are genes that play important roles in inhibiting the process...
<p>Genome-wide DNase-Seq identifies (DHS) regulatory elements in the cell culture sample from our st...
We are investigating the molecular basis of melanoma by defining genomic characteristics that correl...
BACKGROUND: We are investigating the molecular basis of melanoma by defining genomic characteristics...
Human metastatic cutaneous melanoma has gained a well deserved reputation for its immune responsiven...
In order to identify genes relevant for melanoma development, we carried out cDNA array experiments ...
Abstract Human metastatic cutaneous melanoma has gained a well deserved reputation for its immune re...
In spite of intensive and increasingly successful attempts to determine the multiple steps involved ...
In order to identify genes relevant for melanoma development, we carried out cDNA array experiments ...
Gene expression profiling has revolutionized our ability to molecularly classify primary human tumor...