The aim of this Ph.D. thesis is to have a better comprehension of the interactions between coupling, slow slip events (SSEs) and the seismic ruptures in subduction zones. This work focuses on the North Chile - South Peru subduction zone that has been recognized as a mature seismic gap. Thus, the region has been the target of an important international effort in geophysical instrumentation (GPS and seismological stations), since the mid-2000s. The region has been affected by several well-registered earthquakes, that makes it good case to study the earthquake preparation phase and the relationship between coupling, SSE and seismic rupture.The 65 stations available in the region have been processed in double differences using the GAMIT-GLOBK s...