Overweight and obesity are major risk factors for development of non-alcoholic fatty liver disease (NAFLD) and non-response to antiviral therapy in chronic hepatitis C (HCV). The overall aim of this thesis was to elucidate key inflammatory and metabolic genes associated with liver injury and non-response to antiviral therapy in obesity. To achieve this, key inflammatory factors were studied in three compartments: the peripheral blood, adipose tissue and the liver.With respect to the peripheral blood, increased expression of SOCS3 in obese non-responders to antiviral therapy for chronic HCV was found. Increased SOCS3 expression was associated with reduced anti-HCV effector cytokine production and enhanced IL-6 production. Ex vivo experiments...
Over the last few years, the paradigm in hepatology has changed from focusing on a single liver dise...
The aim of this paper is to review and up to date the prevalence of hepatitis C virus (HCV)-associat...
Background Steatosis and insulin resistance (IR) have a pathogenic role in chronic hepatitis C (HCV)...
Obesity and fatty liver are commonly observed among patients with chronic hepatitis C virus (HCV) an...
<div><p>Hepatitis C virus infection leads to a wide spectrum of liver diseases ranging from mild chr...
BACKGROUND: Obesity modulates inflammation and activation of immune pathways which can lead to liver...
Obesity modulates inflammation and activation of immune pathways which can lead to liver complicatio...
Hepatitis C virus infection leads to a wide spectrum of liver diseases ranging from mild chronic hep...
Hepatitis C Virus (HCV) is a significant global health issue that leads to the development of chroni...
Hepatitis C virus (HCV) is one of the main causes of liver disease worldwide. Liver steatosis is a c...
Nonalcoholic fatty liver disease (NAFLD) and hepatitis C virus (HCV)-related liver disease are commo...
Hepatitis C virus (HCV) infects millions of people worldwide and is one of the leading causes of liv...
Nonalcoholic fatty liver disease (NAFLD) and hepatitis C virus (HCV)-related liver disease are commo...
BACKGROUND: Steatosis and insulin resistance (IR) have a pathogenic role in chronic hepatitis C (HCV...
Abnormal accumulation of fat in the liver (steatosis) is commonly observed in hepatitis C virus (HCV...
Over the last few years, the paradigm in hepatology has changed from focusing on a single liver dise...
The aim of this paper is to review and up to date the prevalence of hepatitis C virus (HCV)-associat...
Background Steatosis and insulin resistance (IR) have a pathogenic role in chronic hepatitis C (HCV)...
Obesity and fatty liver are commonly observed among patients with chronic hepatitis C virus (HCV) an...
<div><p>Hepatitis C virus infection leads to a wide spectrum of liver diseases ranging from mild chr...
BACKGROUND: Obesity modulates inflammation and activation of immune pathways which can lead to liver...
Obesity modulates inflammation and activation of immune pathways which can lead to liver complicatio...
Hepatitis C virus infection leads to a wide spectrum of liver diseases ranging from mild chronic hep...
Hepatitis C Virus (HCV) is a significant global health issue that leads to the development of chroni...
Hepatitis C virus (HCV) is one of the main causes of liver disease worldwide. Liver steatosis is a c...
Nonalcoholic fatty liver disease (NAFLD) and hepatitis C virus (HCV)-related liver disease are commo...
Hepatitis C virus (HCV) infects millions of people worldwide and is one of the leading causes of liv...
Nonalcoholic fatty liver disease (NAFLD) and hepatitis C virus (HCV)-related liver disease are commo...
BACKGROUND: Steatosis and insulin resistance (IR) have a pathogenic role in chronic hepatitis C (HCV...
Abnormal accumulation of fat in the liver (steatosis) is commonly observed in hepatitis C virus (HCV...
Over the last few years, the paradigm in hepatology has changed from focusing on a single liver dise...
The aim of this paper is to review and up to date the prevalence of hepatitis C virus (HCV)-associat...
Background Steatosis and insulin resistance (IR) have a pathogenic role in chronic hepatitis C (HCV)...