Survival after yttrium-90 resin microsphere radioembolization of hepatocellular carcinoma across Barcelona clinic liver cancer stages: a European evaluation.
- Sangro B
- Carpanese L
- Cianni R
- Golfieri R
- Gasparini D
- Ezziddin S
- Paprottka PM
- Fiore F
- Van Buskirk M
- Bilbao JI
- Ettorre GM
- Salvatori R
- Giampalma E
- Geatti O
- Wilhelm K
- Hoffmann RT
- Izzo F
- I\uf1arrairaegui M
- Maini CL
- Urigo C
- Cappelli A
- Vit A
- Ahmadzadehfar H
- Jakobs TF
- Lastoria S
- Arbizu J
- Benito A
- Bilbao JI
- D'Avola D
- I\uf1arrairaegui M
- Rodriguez M
- Sangro B
- Carpanese L
- Ettorre GM
- Maini CL
- Milella M
- Pizzi G
- Sciuto R
- Vennarecci G
- Angelelli B
- Blotta A
- Cappelli A
- Giampalma E
- Golfieri R
- Mosconi C
- Pettinato C
- Ferretti G
- Gasparini D
- Geatti O
- Manazzone O
- Soardo G
- Toniutto P
- Vit A
- Bagni O
- Cianni R
- D'Agostini A
- Notarianni E
- Saltarelli A
- Salvatori R
- Urigo C
- Albino V
- Aloy L
- Arrichiello C
- D'Angelo R
- Fiore F
- Izzo F
- Lastoria S
- Ahmadzadehfar H
- Ezziddin S
- Meyer C
- Palmedo H
- Schild HH
- Schmitz V
- Wilhelm K
- Bartenstein P
- Haug AR
- Hoffmann RT
- Jakobs TF
- Kolligs FT
- Paprottka PM
- Trumm, C
- Toniutto, P.
DOIAbstract
A multicenter analysis was conducted to evaluate the main prognostic factors driving survival after radioembolization using yttrium-90-labeled resin microspheres in patients with hepatocellular carcinoma at eight European centers. In total, 325 patients received a median activity of 1.6 GBq between September 2003 and December 2009, predominantly as whole-liver (45.2%) or right-lobe (38.5%) infusions. Typically, patients were Child-Pugh class A (82.5%), had underlying cirrhosis (78.5%), and had good Eastern Cooperative Oncology Group (ECOG) performance status (ECOG 0-1; 87.7%), but many had multinodular disease (75.9%) invading both lobes (53.1%) and/or portal vein occlusion (13.5% branch; 9.8% main). Over half had advanced Barcelona Clinic ...
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