We say that a Turing machine has periodic support if there is an infinitely repeated word to the left of the input and another infinitely repeated word to the right. In the search for the smallest universal Turing machines, machines that use periodic support have been significantly smaller than those for the standard model (i.e. machines with the usual blank tape on either side of the input). While generalising the model allows us to construct smaller universal machines it makes proving decidability results for the various state-symbol products that restrict program size more difficult. Here we show that given an arbitrary 2-state 2-symbol Turing machine and a configuration with periodic support the set of reachable configurations is regula...