BACKGROUND: Amylin is a pancreatic β-cell hormone that produces effects in several different organ systems. One of its best-characterized effects is the reduction in eating and body weight seen in preclinical and clinical studies. Amylin activates specific receptors, a portion of which it shares with calcitonin gene-related peptide (CGRP). Amylin's role in the control of energy metabolism relates to its satiating effect, but recent data indicate that amylin may also affect hedonic aspects in the control of eating, including a reduction of the rewarding value of food. Recently, several amylin-based peptides have been characterized. Pramlintide (Symlin®) is currently the only one being used clinically to treat type 1 and type 2 diabetes. Howe...
and Johan Permert. Amylin Receptor Blockade Stimulates Food Intake in Rats. Amylin is postulated to ...
Amylin, also known as islet amyloid polypeptide, is co-secreted with insulin by pancreatic β-cells i...
Evidence from rodent studies indicates that the -cell-derived neurohormone amylin exerts multiple ef...
Background: Amylin is a pancreatic β-cell hormone that produces effects in several different organ s...
Amylin is an important control of nutrient fluxes because it reduces energy intake, modulates nutrie...
Amylin (also called islet amyloid polypeptide (IAPP)) is a pancreatic beta-cell hormone that is co-s...
Amylin controls nutrient fluxes by reducing food intake, slowing gastric emptying and reducing postp...
This paper is based on a presentation given at the Annual Meeting of the Society for the Study of In...
Amylin, also known as islet amyloid polypeptide, identified in 1987, is a naturally occurring hormon...
The control of meal size is the best studied aspect of the control of energy balance, and manipulati...
The prevalence of obesity and associated comorbidities such as type 2 diabetes and cardiovascular di...
This article in the Neural and Endocrine Section of Comprehensive Physiology discusses the physiolog...
Amylin is secreted by pancreatic beta-cells and seems to function as a physiological signal of satia...
Amylin is a polypeptide that is cosecreted with insulin from the beta cells of the pancreas. Therefo...
The hypothalamic arcuate nucleus (ARC) and the area postrema (AP) represent targets for hormonal and...
and Johan Permert. Amylin Receptor Blockade Stimulates Food Intake in Rats. Amylin is postulated to ...
Amylin, also known as islet amyloid polypeptide, is co-secreted with insulin by pancreatic β-cells i...
Evidence from rodent studies indicates that the -cell-derived neurohormone amylin exerts multiple ef...
Background: Amylin is a pancreatic β-cell hormone that produces effects in several different organ s...
Amylin is an important control of nutrient fluxes because it reduces energy intake, modulates nutrie...
Amylin (also called islet amyloid polypeptide (IAPP)) is a pancreatic beta-cell hormone that is co-s...
Amylin controls nutrient fluxes by reducing food intake, slowing gastric emptying and reducing postp...
This paper is based on a presentation given at the Annual Meeting of the Society for the Study of In...
Amylin, also known as islet amyloid polypeptide, identified in 1987, is a naturally occurring hormon...
The control of meal size is the best studied aspect of the control of energy balance, and manipulati...
The prevalence of obesity and associated comorbidities such as type 2 diabetes and cardiovascular di...
This article in the Neural and Endocrine Section of Comprehensive Physiology discusses the physiolog...
Amylin is secreted by pancreatic beta-cells and seems to function as a physiological signal of satia...
Amylin is a polypeptide that is cosecreted with insulin from the beta cells of the pancreas. Therefo...
The hypothalamic arcuate nucleus (ARC) and the area postrema (AP) represent targets for hormonal and...
and Johan Permert. Amylin Receptor Blockade Stimulates Food Intake in Rats. Amylin is postulated to ...
Amylin, also known as islet amyloid polypeptide, is co-secreted with insulin by pancreatic β-cells i...
Evidence from rodent studies indicates that the -cell-derived neurohormone amylin exerts multiple ef...