Homeostasis of osteoclast formation from bone marrow macrophages (BMM) is regulated by paracrine signals of the neighbourhood bone cells particularly mesenchymal stem cells (MSC), osteoblasts and osteocytes (OC). Besides paracrine cues, collagen and glycosaminoglycan are involved in controlling bone homeostasis. Towards this approach, different molecular weight collagens were reacted with MSC, OC and BMM to understand the bone homeostasis activity of collagen. The up-regulating effect of collagens on osteogenic cell growth was confirmed by the presence of mineralized nodules in the osteoblastogenic lineage cells and increased osteogenic stimulatory gene expression. The decreased BMM-derived TRAP+ osteoclasts number and osteoclastogenic regu...
Collagen is the main protein component of the extracellular matrix of bone, and it has structural an...
OBJECTIVES Osteoclasts rapidly form on the surface of bone chips at augmentation sites. The under...
Osteoimmunology as an interdisciplinary research principle governing the cross-talk between the skel...
Collagen has been widely shown to promote osteogenesis of bone marrow mesenchymal stromal cells (BM-...
Human multipotent mesenchymal stromal cells (hMSCs) are multipotent cells that, in the presence of a...
The effect of mesenchymal stem cells (MSCs) on bone formation has been extensively demonstrated thro...
Introduction Osteoclasts are bone-resorbing cells closely related to bone turnover, whereas differen...
Biomineralized collagen with intrafibrillar calcium phosphate mineral provides an excellent mimic of...
<div><p>In bone, depletion of osteoclasts reduces bone formation <i>in vivo</i>, as does osteal macr...
In bone, depletion of osteoclasts reduces bone formation in vivo, as does osteal macrophage depletio...
Heterotypic cell interactions are essential for the homeostasis of bone tissue, in particular the wi...
Human multipotent mesenchymal stromal cells (hMSCs) are multipotent cells that, in the presence of a...
Recent studies have identified the regulatory mechanism of collagen in bone ossification and resorpt...
Biomineralized collagen with intrafibrillar calcium phosphate mineral provides an excellent mimic of...
Abstract onlyWe have used a culture system of human peripheral blood mononuclear cells (PBMC)as a so...
Collagen is the main protein component of the extracellular matrix of bone, and it has structural an...
OBJECTIVES Osteoclasts rapidly form on the surface of bone chips at augmentation sites. The under...
Osteoimmunology as an interdisciplinary research principle governing the cross-talk between the skel...
Collagen has been widely shown to promote osteogenesis of bone marrow mesenchymal stromal cells (BM-...
Human multipotent mesenchymal stromal cells (hMSCs) are multipotent cells that, in the presence of a...
The effect of mesenchymal stem cells (MSCs) on bone formation has been extensively demonstrated thro...
Introduction Osteoclasts are bone-resorbing cells closely related to bone turnover, whereas differen...
Biomineralized collagen with intrafibrillar calcium phosphate mineral provides an excellent mimic of...
<div><p>In bone, depletion of osteoclasts reduces bone formation <i>in vivo</i>, as does osteal macr...
In bone, depletion of osteoclasts reduces bone formation in vivo, as does osteal macrophage depletio...
Heterotypic cell interactions are essential for the homeostasis of bone tissue, in particular the wi...
Human multipotent mesenchymal stromal cells (hMSCs) are multipotent cells that, in the presence of a...
Recent studies have identified the regulatory mechanism of collagen in bone ossification and resorpt...
Biomineralized collagen with intrafibrillar calcium phosphate mineral provides an excellent mimic of...
Abstract onlyWe have used a culture system of human peripheral blood mononuclear cells (PBMC)as a so...
Collagen is the main protein component of the extracellular matrix of bone, and it has structural an...
OBJECTIVES Osteoclasts rapidly form on the surface of bone chips at augmentation sites. The under...
Osteoimmunology as an interdisciplinary research principle governing the cross-talk between the skel...