Relationship between exposure to particulate matter and biomarkers among bus driver In Klang Valley.

This cross-sectional comparative study investigates the association between particulate matters (PM; PM10, PM2.5 and ultrafine particle (UFP) and concentration of biomarkers; Interleukin-6 (IL-6) and Tumor Necrosis Factor- Alpha (TNF-α) using 62 bus drivers as exposed group and 62 administrative staff as comparative group in Klang Valley, Malaysia. T-test results showed that the mean exposure level of PM10 (t = 8.14, p<0.01), PM2.5 (t = 9.95, p<0.01) and UFP (t = 19.61, p<0.01) were significantly higher among the bus drivers compared to comparative group. Mann-Whitney U test of IL-6 (z = -2.43, p<0.05) and TNF-α (z = -5.88, p