Add to ORKGObjective: Fetal cells and circulating cellfree fetal DNA increases in the maternal circulation in women carrying trisomy 21 fetus. Methods: We attempted the use of superoxide dismutase (SOD-1) gene, which is located at the Down Syndrome Critical Region, to overcome this situation for the prenatal screening of Down syndrome. The prospective of the gene using real-time quantitative polymerase chain reaction was explored. Results: The level of SOD-1 sequences is significantly elevated in the third trimester normal pregnancies (mean = 11728 copies/μl) when compared to the second trimester (mean = 5705.6 copies/μl), (p<0.005) and non pregnant normal women (mean = 3580.2 copies/μl), (p<0.0001). Down syndrome pregnancies have the greates...
†Authors contributed equally to the work. Objective To develop a novel prenatal assay based on selec...
Introduction: Down syndrome is a predominant genetic disease with an incident rate of one in every 7...
OBJECTIVE: Analysis of the levels of cell-free fetal and total DNA in serum of women carrying a male...
It has been shown that fetal cells and circulating cellfree fetal DNA increases in the maternal circ...
The present invention provides a method using polymerasa chain reaction (PCR) for detecting Down syn...
Down Syndrome (DS), also called trisomy 21, is the most common non- lethal fetal aneuploidy that aff...
Prenatal diagnosis still depends on invasive methods using cells contained in the amniotic fluid or ...
Background Screening tests for Trisomy 21 (T21), also known as Down syndrome, are routinely perfo...
Objective: To quantify circulating fetal DNA (fDNA) levels in the second and third trimesters of nor...
BACKGROUND: Prenatal screening for Down's syndrome is performed using biochemical and ultrasound mar...
PMCID: PMC3604109This is an open-access article distributed under the terms of the Creative Commons ...
<div><p>Background</p><p>Prenatal screening for Down's syndrome is performed using biochemical and u...
Prenatal screening for Down's syndrome is performed using biochemical and ultrasound markers measure...
Background Prenatal diagnosis of chromosomal abnormality requires cytogenetic analysis of amniotic f...
†Authors contributed equally to the work. Objective To develop a novel prenatal assay based on selec...
†Authors contributed equally to the work. Objective To develop a novel prenatal assay based on selec...
Introduction: Down syndrome is a predominant genetic disease with an incident rate of one in every 7...
OBJECTIVE: Analysis of the levels of cell-free fetal and total DNA in serum of women carrying a male...
It has been shown that fetal cells and circulating cellfree fetal DNA increases in the maternal circ...
The present invention provides a method using polymerasa chain reaction (PCR) for detecting Down syn...
Down Syndrome (DS), also called trisomy 21, is the most common non- lethal fetal aneuploidy that aff...
Prenatal diagnosis still depends on invasive methods using cells contained in the amniotic fluid or ...
Background Screening tests for Trisomy 21 (T21), also known as Down syndrome, are routinely perfo...
Objective: To quantify circulating fetal DNA (fDNA) levels in the second and third trimesters of nor...
BACKGROUND: Prenatal screening for Down's syndrome is performed using biochemical and ultrasound mar...
PMCID: PMC3604109This is an open-access article distributed under the terms of the Creative Commons ...
<div><p>Background</p><p>Prenatal screening for Down's syndrome is performed using biochemical and u...
Prenatal screening for Down's syndrome is performed using biochemical and ultrasound markers measure...
Background Prenatal diagnosis of chromosomal abnormality requires cytogenetic analysis of amniotic f...
†Authors contributed equally to the work. Objective To develop a novel prenatal assay based on selec...
†Authors contributed equally to the work. Objective To develop a novel prenatal assay based on selec...
Introduction: Down syndrome is a predominant genetic disease with an incident rate of one in every 7...
OBJECTIVE: Analysis of the levels of cell-free fetal and total DNA in serum of women carrying a male...