<p>The replication-competent virus HCV-Luc was used to infect parental Huh7.5 cells transfected with either siControl or siTACSTD2, or cotransfected with siTACSTD2 plus an expression vector encoding siRNA-resistant TACSTD2 (pTACSTD2). The AR4A neutralizing anti-HCV envelope monoclonal antibody (50 μg/mL), as well as the inhibitor of HCV replication, cyclosporin A (CsA; 10 μM) and DMSO (solvent of CsA) served as controls. At 24h, 48h, and 72h post-infection the cells were lysed, and viral replication was assessed by measurement of luciferase reporter gene activity. Values are normalized to relative light unit (RLU) from siControl-treated cells (raw RLU values [mean ± SEM] for siC: 24h, 3390 ± 264; 48h, 74397 ± 2744; 72h, 16107 ± 1603) and re...
<p>MRC-5 cells were untreated or transfected with 50 nM of non-specific scrambled control siRNA (siS...
<p>Huh7.5 cells were transfected with the negative control siRNA (NC) or the Rubicon (Rb) siRNA for ...
<p>A) Mock- and HCV-infected cells were transfected with 500 ng of pLucTKS3, p3x-κB-Luc, or (AP-1)<s...
<p>Parental Huh7.5 cells were transfected with either siControl or siTACSTD2 and after 72 h were inf...
<p>(A) Parental Huh7.5 cells were transfected with either siControl or siTACSTD2 for 72h before infe...
<p>(A) Knockdown of PC had no effect on viral protein levels in HCV replicon cells. Huh7 cells harbo...
<p>MRC-5 cells were transfected with 50 nM of non-specific scrambled control siRNA (siSc) or siRNAs ...
<p>Huh-7.5 cells were transfected with PLA2G4A-specific or scrambled siRNAs. 96 h later cells were i...
<p>(A) MRC-5 cells were untreated or transfected with 50 nM of non-specific scrambled control siRNA ...
<p>Parental and TACSTD2 overexpressing Huh7.5 cells were infected with HCV 1a, 1b, 2b, 3a, 4a, 5a, 6...
<p>(A) Inhibition of TSG101, Alix, Vps4B, or CHMP4b protein expression by shRNA-producing lentiviral...
<p>(A) Huh 7.5.1 cells were transfected with oligonucleotides to knockdown expression of SDC1 (siSDC...
<p>MRC-5 cells were untreated or transfected with 50 nM of non-specific scrambled control siRNA (siS...
<p>MRC-5 cells were transfected with 50 nM of non-specific scrambled control siRNA (siSc) or siRNAs ...
<p>(A) Huh7 cells were infected with HCVpp in the presence and absence of OPC or sPLA2IIA inhibitor ...
<p>MRC-5 cells were untreated or transfected with 50 nM of non-specific scrambled control siRNA (siS...
<p>Huh7.5 cells were transfected with the negative control siRNA (NC) or the Rubicon (Rb) siRNA for ...
<p>A) Mock- and HCV-infected cells were transfected with 500 ng of pLucTKS3, p3x-κB-Luc, or (AP-1)<s...
<p>Parental Huh7.5 cells were transfected with either siControl or siTACSTD2 and after 72 h were inf...
<p>(A) Parental Huh7.5 cells were transfected with either siControl or siTACSTD2 for 72h before infe...
<p>(A) Knockdown of PC had no effect on viral protein levels in HCV replicon cells. Huh7 cells harbo...
<p>MRC-5 cells were transfected with 50 nM of non-specific scrambled control siRNA (siSc) or siRNAs ...
<p>Huh-7.5 cells were transfected with PLA2G4A-specific or scrambled siRNAs. 96 h later cells were i...
<p>(A) MRC-5 cells were untreated or transfected with 50 nM of non-specific scrambled control siRNA ...
<p>Parental and TACSTD2 overexpressing Huh7.5 cells were infected with HCV 1a, 1b, 2b, 3a, 4a, 5a, 6...
<p>(A) Inhibition of TSG101, Alix, Vps4B, or CHMP4b protein expression by shRNA-producing lentiviral...
<p>(A) Huh 7.5.1 cells were transfected with oligonucleotides to knockdown expression of SDC1 (siSDC...
<p>MRC-5 cells were untreated or transfected with 50 nM of non-specific scrambled control siRNA (siS...
<p>MRC-5 cells were transfected with 50 nM of non-specific scrambled control siRNA (siSc) or siRNAs ...
<p>(A) Huh7 cells were infected with HCVpp in the presence and absence of OPC or sPLA2IIA inhibitor ...
<p>MRC-5 cells were untreated or transfected with 50 nM of non-specific scrambled control siRNA (siS...
<p>Huh7.5 cells were transfected with the negative control siRNA (NC) or the Rubicon (Rb) siRNA for ...
<p>A) Mock- and HCV-infected cells were transfected with 500 ng of pLucTKS3, p3x-κB-Luc, or (AP-1)<s...