Eosinophilia does not impact on expansion of arginase-expressing AAMϕ but augments RELMα production.

<p>Expansion of peritoneal Mϕ in BALB/c WT, ΔdblGATA deficient mice or CCR3 deficient mice <b>(A,B)</b> or in WT mice treated ip with rat IgG control or rat αCCR3 <b>(C,D)</b> at indicated time points post-ip infection with 50 <i>Bm</i>L3. Arginase activity in PC cells from BALB/c WT, ΔdblGATA deficient or CCR3 deficient mice, WT mice treated ip with rat IgG control or rat αCCR3 <b>(E)</b> and expression of <i>arg1</i> in purified Mϕ from WT mice treated ip with IgG control or αCCR3 <b>(F)</b> at indicated time points post-ip infection with 50 <i>Bm</i>L3. F4/80 peritoneal Mϕ expression levels of RELMα in BALB/c WT or CCR3^-/- mice at +14 day post-infection with 50 <i>Bm</i>L3 <b>(G,H)</b>. Data from individual mice with median and interquartile range are plotted. Significant differences between groups assessed by Mann-Whitney or Kruskal-Wallis + Dunn’s tests (>2 groups). Data is from an individual experiment or pooled from 2–3 individual experiments per time-point using groups of 3–6 mice per group / time-point.