WMHv burden and DTI indices within NAWM and WMH.

<p>Figure shows results of Spearman correlations (rho) between WMH volume (WMHv) and DTI indices within areas of NAWM (top panels) and WMH (bottom panels) on baseline data. The x-axes represent WMHv expressed as percent of the intracranial cavity volume (ICV). The y-axes represent the DTI indices, namely the FA (left two panels, black circles) and AD and RD (right two panels, blue and red circles, respectively). Circles represent the average value within supratentorial NAWM or WMH areas for each study subject. Correlation remained significant after controlling for age and gender. Lines represent a fitted linear regression trendline.