Sustained glucagon effect on blood glucose regulation.

<p>The blood glucose lowering effect of 86 nmol/kg (A and B) and 120 nmol/kg (C and D) insulin ± 1 nmol/kg LAG during the light period. The change in blood glucose plotted as a function of time (A and C). The maximum change from baseline (B and D). Data are expressed as means of 5 days (86 nmol/kg insulin) and 2 days (86 nmol/kg insulin + 1nmol/kg LAG, 120 nmol/kg ± 1nmol/kg LAG), respectively ± SEM; n = 4–8. A significant effect of adding 1 nmol/kg LAG to both 86 nmol/kg and 120 nmol/kg insulin is indicated by ** (p < 0.003) (analyzed using a two-tailed paired t-test).