Effect of gauze combined with water bag packing on the coagulation function, RAS system and stress response of patients with placenta previa complicated with postpartum hemorrhage

Objective: To study the effect of gauze combined with water bag packing on the coagulation function, RAS system and stress response of patients with placenta previa complicated with postpartum hemorrhage. Methods: A total of 69 patients with placenta previa complicated with postpartum hemorrhage who were treated in the hospital between March 2013 and September 2016 were selected and randomly divided into the research group who accepted gauze combined with water bag packing, the control group A who accepted gauze packing and the control group B who accepted water bag packing. The coagulation function indexes, RAS system indexes and stress response indexes were measured 12 h after delivery. Results: D-D, FDP, REN, AT-II, ALD, NE, E, MDA and ET-1 contents as well as APTT, TT and PT levels of research group 12 hours after delivery were lower than those of control group A and control group B, and D-D, FDP, REN, AT-II, ALD, NE, E, MDA and ET-1 contents as well as APTT, TT and PT levels of control group A were not significantly different from those of control group B. Conclusion: Gauze combined with water bag packing for placenta previa complicated with postpartum hemorrhage can improve the coagulation function and inhibit the excessive activation of RAS system and stress response