Additional file 2: of Knockdown delta-5-desaturase in breast cancer cells that overexpress COX-2 results in inhibition of growth, migration and invasion via a dihomo-γ-linolenic acid peroxidation dependent mechanism

Additional file 5: of Dihomo-Îł-linolenic acid inhibits xenograft tumor growth in mice bearing shRNA-transfected HCA-7 cells targeting delta-5-desaturase

Yi Xu (131145)
Xiaoyu Yang (547580)
Di Gao (501357)
Liu Yang (23752)
Keith Miskimins (5022932)
Steven Qian (5022929)

December 2018

Figure S2. Body weight of mice bearing HCA-7 xenograft tumors during 4-week treatment. A. Measured b...

Additional file 7: of Isocitrate dehydrogenase 1âsnail axis dysfunction significantly correlates with breast cancer prognosis and regulates cell invasion ability

Wen-Shan Liu (644329)
Shih-Hsuan Chan (5107190)
Hong-Tai Chang (676127)
Guan-Cheng Li (265574)
Ya-Ting Tu (5107184)
Hui-Hwa Tseng (672148)
Ting-Ying Fu (4060324)
Hui-Yu Chang (5107187)
Huei-Han Liou (3459209)
Luo-Ping Ger (3459227)
Kuo-Wang Tsai (3459218)

April 2018

Figure S3. IDH1 stable knockdown significantly promoted MDA-MB-231 cell motility. (a) The expression...

Additional file 2: of Adipocyte-derived IL-6 and leptin promote breast Cancer metastasis via upregulation of Lysyl Hydroxylase-2 expression

Jin-Yong He (6100892)
Xiao-Hui Wei (6100895)
Si-Jing Li (6100898)
Yang Liu (4829)
Hao-Lin Hu (6100901)
Zheng-Zheng Li (1637104)
Xin-Hong Kuang (6100904)
Lai Wang (23747)
Xin Shi (139139)
Sheng-Tao Yuan (6100907)
Li Sun (4624)

December 2018

Figure S1. Collagen and PLOD2 expression were significantly increased following coculture with adipo...

Additional file 1: of Knockdown delta-5-desaturase in breast cancer cells that overexpress COX-2 results in inhibition of growth, migration and invasion via a dihomo-γ-linolenic acid peroxidation dependent mechanism

Yi Xu (131145)
Xiaoyu Yang (547580)
Tao Wang (12008)
Liu Yang (23752)
Yu-Ying He (825880)
Keith Miskimins (5022932)
Steven Qian (5022929)

March 2018

Figure S1. GC/MS quantification of 8-HOA from Nc-si, D5D-KD and D5D/COX-2 double-KD MDA-MB 231/4 T1 ...

Additional file 3: of Knockdown delta-5-desaturase in breast cancer cells that overexpress COX-2 results in inhibition of growth, migration and invasion via a dihomo-γ-linolenic acid peroxidation dependent mechanism

Yi Xu (131145)
Xiaoyu Yang (547580)
Tao Wang (12008)
Liu Yang (23752)
Yu-Ying He (825880)
Keith Miskimins (5022932)
Steven Qian (5022929)

March 2018

Table S1. LC/MS quantification of DGLA and AA from Nc-si MB 231, D5D-KD MB 231, Nc-si 4 T1 or D5D-KD...

Additional file 4: of Knockdown delta-5-desaturase in breast cancer cells that overexpress COX-2 results in inhibition of growth, migration and invasion via a dihomo-γ-linolenic acid peroxidation dependent mechanism

Yi Xu (131145)
Xiaoyu Yang (547580)
Tao Wang (12008)
Liu Yang (23752)
Yu-Ying He (825880)
Keith Miskimins (5022932)
Steven Qian (5022929)

March 2018

Figure S3. HDAC activity assay of D5D-KD 4 T1 and D5D-KD MDA-MB-231 cells treated with vehicle or DG...

Additional file 2: Figure S2. of 5-lipoxygenase mediates docosahexaenoyl ethanolamide and N-arachidonoyl-L-alanine-induced reactive oxygen species production and inhibition of proliferation of head and neck squamous cell carcinoma cells

Seok-Woo Park (3521150)
J. Hah (3521153)
Sang-Mi Oh (3521144)
Woo-Jin Jeong (3521147)
Myung-Whun Sung (668703)

July 2016

Anti-cancer effect of DHEA and NALA was not reversed by inhibition of COX-2. (PPTX 75Â kb

Additional file 1: of Dihomo-Îł-linolenic acid inhibits xenograft tumor growth in mice bearing shRNA-transfected HCA-7 cells targeting delta-5-desaturase

Yi Xu (131145)
Xiaoyu Yang (547580)
Di Gao (501357)
Liu Yang (23752)
Keith Miskimins (5022932)
Steven Qian (5022929)

December 2018

Figure S1. D5D-KD alone did not affect HCA-7 cell growth. A. Colony formation of D5D-WT and D5D-KD H...

Additional file 9: of Isocitrate dehydrogenase 1âsnail axis dysfunction significantly correlates with breast cancer prognosis and regulates cell invasion ability

Wen-Shan Liu (644329)
Shih-Hsuan Chan (5107190)
Hong-Tai Chang (676127)
Guan-Cheng Li (265574)
Ya-Ting Tu (5107184)
Hui-Hwa Tseng (672148)
Ting-Ying Fu (4060324)
Hui-Yu Chang (5107187)
Huei-Han Liou (3459209)
Luo-Ping Ger (3459227)
Kuo-Wang Tsai (3459218)

April 2018

Figure S5. IDH1 knockdown accelerated MCF7 cell proliferation and migration ability. (a) the express...

Additional file 2: of Dihomo-γ-linolenic acid inhibits xenograft tumor growth in mice bearing shRNA-transfected HCA-7 cells targeting delta-5-desaturase

Yi Xu (131145)
Xiaoyu Yang (547580)
Di Gao (501357)
Liu Yang (23752)
Keith Miskimins (5022932)
Steven Qian (5022929)

December 2018

Table S1. Statistical analysis (ANOVA) for tumor size in Fig. 4a. The four groups are: Group 1: D5D-...

Additional file 1: of Doxycycline attenuates breast cancer related inflammation by decreasing plasma lysophosphatidate concentrations and inhibiting NF-ÎşB activation

Xiaoyun Tang (3766717)
Xianyan Wang (17873)
Yuan Zhao (336512)
Jonathan Curtis (3766723)
David Brindley (3766720)

February 2017

Effects of doxycycline (Dox) on tumor growth, metastasis, and leukocyteinfiltration. (PPTX 2548Â kb

Additional file 3: Figure S3. of COX-2 modulates mammary tumor progression in response to collagen density

Karla Esbona (3580781)
David Inman (3514316)
Sandeep Saha (589585)
Justin Jeffery (3514328)
Pepper Schedin (3448)
Lee Wilke (3580778)
Patricia Keely (3514319)

March 2016

Celecoxib diminishes COX2 and PGE2. a IHC images of COX-2 and PGE2 (DAB) counterstained with hematox...

Additional file 1: of Elucidating the mechanism of action of domatinostat (4SC-202) in cutaneous T cell lymphoma cells

Marion Wobser (515061)
Alexandra Weber (3661234)
Amelie Glunz (6478181)
Saskia Tauch (6478184)
Kristina Seitz (6478187)
Tobias Butelmann (6478190)
Sonja Hesbacher (348437)
Matthias Goebeler (475952)
René Bartz (6478202)
Hella Kohlhof (480871)
David Schrama (273819)
Roland Houben (96277)

March 2019

Table S1. Doubling time in hours of the investigated cell lines and fibroblasts B. Table S2. Real ti...

Additional file 2: Figure S2. of COX-2 modulates mammary tumor progression in response to collagen density

Karla Esbona (3580781)
David Inman (3514316)
Sandeep Saha (589585)
Justin Jeffery (3514328)
Pepper Schedin (3448)
Lee Wilke (3580778)
Patricia Keely (3514319)

March 2016

COX-2 inhibition and lung metastasis. a Lung metastases tend to be increased in PyMT/Cola1a tumors a...

Additional file 2: of CD36 mediates palmitate acid-induced metastasis of gastric cancer via AKT/GSK-3β/β-catenin pathway

Jiaomeng Pan (6295748)
Zhiyuan Fan (1934725)
Zhenqiang Wang (1459963)
Qingqiang Dai (6295751)
Zhen Xiang (5351870)
Fei Yuan (24924)
Min Yan (119568)
Zhenggang Zhu (297842)
Bingya Liu (170981)
Chen Li (54018)

February 2019

Figure S1. Effect of SA, OA and DHA on metastasis of GC cells. (a) and (b) Effect of different conce...

Additional file 5: of Dihomo-Îł-linolenic acid inhibits xenograft tumor growth in mice bearing shRNA-transfected HCA-7 cells targeting delta-5-desaturase

Yi Xu (131145)
Xiaoyu Yang (547580)
Di Gao (501357)
Liu Yang (23752)
Keith Miskimins (5022932)
Steven Qian (5022929)

December 2018

Figure S2. Body weight of mice bearing HCA-7 xenograft tumors during 4-week treatment. A. Measured b...

Additional file 7: of Isocitrate dehydrogenase 1âsnail axis dysfunction significantly correlates with breast cancer prognosis and regulates cell invasion ability

Wen-Shan Liu (644329)
Shih-Hsuan Chan (5107190)
Hong-Tai Chang (676127)
Guan-Cheng Li (265574)
Ya-Ting Tu (5107184)
Hui-Hwa Tseng (672148)
Ting-Ying Fu (4060324)
Hui-Yu Chang (5107187)
Huei-Han Liou (3459209)
Luo-Ping Ger (3459227)
Kuo-Wang Tsai (3459218)

April 2018

Figure S3. IDH1 stable knockdown significantly promoted MDA-MB-231 cell motility. (a) The expression...

Additional file 2: of Adipocyte-derived IL-6 and leptin promote breast Cancer metastasis via upregulation of Lysyl Hydroxylase-2 expression

Jin-Yong He (6100892)
Xiao-Hui Wei (6100895)
Si-Jing Li (6100898)
Yang Liu (4829)
Hao-Lin Hu (6100901)
Zheng-Zheng Li (1637104)
Xin-Hong Kuang (6100904)
Lai Wang (23747)
Xin Shi (139139)
Sheng-Tao Yuan (6100907)
Li Sun (4624)

December 2018

Figure S1. Collagen and PLOD2 expression were significantly increased following coculture with adipo...

Additional file 1: of Knockdown delta-5-desaturase in breast cancer cells that overexpress COX-2 results in inhibition of growth, migration and invasion via a dihomo-γ-linolenic acid peroxidation dependent mechanism

Yi Xu (131145)
Xiaoyu Yang (547580)
Tao Wang (12008)
Liu Yang (23752)
Yu-Ying He (825880)
Keith Miskimins (5022932)
Steven Qian (5022929)

March 2018

Figure S1. GC/MS quantification of 8-HOA from Nc-si, D5D-KD and D5D/COX-2 double-KD MDA-MB 231/4 T1 ...

Additional file 3: of Knockdown delta-5-desaturase in breast cancer cells that overexpress COX-2 results in inhibition of growth, migration and invasion via a dihomo-γ-linolenic acid peroxidation dependent mechanism

Yi Xu (131145)
Xiaoyu Yang (547580)
Tao Wang (12008)
Liu Yang (23752)
Yu-Ying He (825880)
Keith Miskimins (5022932)
Steven Qian (5022929)

March 2018

Table S1. LC/MS quantification of DGLA and AA from Nc-si MB 231, D5D-KD MB 231, Nc-si 4 T1 or D5D-KD...

Additional file 4: of Knockdown delta-5-desaturase in breast cancer cells that overexpress COX-2 results in inhibition of growth, migration and invasion via a dihomo-γ-linolenic acid peroxidation dependent mechanism

Yi Xu (131145)
Xiaoyu Yang (547580)
Tao Wang (12008)
Liu Yang (23752)
Yu-Ying He (825880)
Keith Miskimins (5022932)
Steven Qian (5022929)

March 2018

Figure S3. HDAC activity assay of D5D-KD 4 T1 and D5D-KD MDA-MB-231 cells treated with vehicle or DG...

Additional file 2: Figure S2. of 5-lipoxygenase mediates docosahexaenoyl ethanolamide and N-arachidonoyl-L-alanine-induced reactive oxygen species production and inhibition of proliferation of head and neck squamous cell carcinoma cells

Seok-Woo Park (3521150)
J. Hah (3521153)
Sang-Mi Oh (3521144)
Woo-Jin Jeong (3521147)
Myung-Whun Sung (668703)

July 2016

Anti-cancer effect of DHEA and NALA was not reversed by inhibition of COX-2. (PPTX 75Â kb

Additional file 1: of Dihomo-Îł-linolenic acid inhibits xenograft tumor growth in mice bearing shRNA-transfected HCA-7 cells targeting delta-5-desaturase

Yi Xu (131145)
Xiaoyu Yang (547580)
Di Gao (501357)
Liu Yang (23752)
Keith Miskimins (5022932)
Steven Qian (5022929)

December 2018

Figure S1. D5D-KD alone did not affect HCA-7 cell growth. A. Colony formation of D5D-WT and D5D-KD H...

Additional file 9: of Isocitrate dehydrogenase 1âsnail axis dysfunction significantly correlates with breast cancer prognosis and regulates cell invasion ability

Wen-Shan Liu (644329)
Shih-Hsuan Chan (5107190)
Hong-Tai Chang (676127)
Guan-Cheng Li (265574)
Ya-Ting Tu (5107184)
Hui-Hwa Tseng (672148)
Ting-Ying Fu (4060324)
Hui-Yu Chang (5107187)
Huei-Han Liou (3459209)
Luo-Ping Ger (3459227)
Kuo-Wang Tsai (3459218)

April 2018

Figure S5. IDH1 knockdown accelerated MCF7 cell proliferation and migration ability. (a) the express...

Additional file 2: of Dihomo-γ-linolenic acid inhibits xenograft tumor growth in mice bearing shRNA-transfected HCA-7 cells targeting delta-5-desaturase

Yi Xu (131145)
Xiaoyu Yang (547580)
Di Gao (501357)
Liu Yang (23752)
Keith Miskimins (5022932)
Steven Qian (5022929)

December 2018

Table S1. Statistical analysis (ANOVA) for tumor size in Fig. 4a. The four groups are: Group 1: D5D-...

Additional file 1: of Doxycycline attenuates breast cancer related inflammation by decreasing plasma lysophosphatidate concentrations and inhibiting NF-ÎşB activation

Xiaoyun Tang (3766717)
Xianyan Wang (17873)
Yuan Zhao (336512)
Jonathan Curtis (3766723)
David Brindley (3766720)

February 2017

Effects of doxycycline (Dox) on tumor growth, metastasis, and leukocyteinfiltration. (PPTX 2548Â kb

Additional file 3: Figure S3. of COX-2 modulates mammary tumor progression in response to collagen density

Karla Esbona (3580781)
David Inman (3514316)
Sandeep Saha (589585)
Justin Jeffery (3514328)
Pepper Schedin (3448)
Lee Wilke (3580778)
Patricia Keely (3514319)

March 2016

Celecoxib diminishes COX2 and PGE2. a IHC images of COX-2 and PGE2 (DAB) counterstained with hematox...

Additional file 1: of Elucidating the mechanism of action of domatinostat (4SC-202) in cutaneous T cell lymphoma cells

Marion Wobser (515061)
Alexandra Weber (3661234)
Amelie Glunz (6478181)
Saskia Tauch (6478184)
Kristina Seitz (6478187)
Tobias Butelmann (6478190)
Sonja Hesbacher (348437)
Matthias Goebeler (475952)
René Bartz (6478202)
Hella Kohlhof (480871)
David Schrama (273819)
Roland Houben (96277)

March 2019

Table S1. Doubling time in hours of the investigated cell lines and fibroblasts B. Table S2. Real ti...

Additional file 2: Figure S2. of COX-2 modulates mammary tumor progression in response to collagen density

Karla Esbona (3580781)
David Inman (3514316)
Sandeep Saha (589585)
Justin Jeffery (3514328)
Pepper Schedin (3448)
Lee Wilke (3580778)
Patricia Keely (3514319)

March 2016

COX-2 inhibition and lung metastasis. a Lung metastases tend to be increased in PyMT/Cola1a tumors a...

Additional file 2: of CD36 mediates palmitate acid-induced metastasis of gastric cancer via AKT/GSK-3β/β-catenin pathway

Jiaomeng Pan (6295748)
Zhiyuan Fan (1934725)
Zhenqiang Wang (1459963)
Qingqiang Dai (6295751)
Zhen Xiang (5351870)
Fei Yuan (24924)
Min Yan (119568)
Zhenggang Zhu (297842)
Bingya Liu (170981)
Chen Li (54018)

February 2019

Figure S1. Effect of SA, OA and DHA on metastasis of GC cells. (a) and (b) Effect of different conce...

Additional file 5: of Dihomo-Îł-linolenic acid inhibits xenograft tumor growth in mice bearing shRNA-transfected HCA-7 cells targeting delta-5-desaturase

Yi Xu (131145)
Xiaoyu Yang (547580)
Di Gao (501357)
Liu Yang (23752)
Keith Miskimins (5022932)
Steven Qian (5022929)

December 2018

Figure S2. Body weight of mice bearing HCA-7 xenograft tumors during 4-week treatment. A. Measured b...

Additional file 7: of Isocitrate dehydrogenase 1âsnail axis dysfunction significantly correlates with breast cancer prognosis and regulates cell invasion ability

Wen-Shan Liu (644329)
Shih-Hsuan Chan (5107190)
Hong-Tai Chang (676127)
Guan-Cheng Li (265574)
Ya-Ting Tu (5107184)
Hui-Hwa Tseng (672148)
Ting-Ying Fu (4060324)
Hui-Yu Chang (5107187)
Huei-Han Liou (3459209)
Luo-Ping Ger (3459227)
Kuo-Wang Tsai (3459218)

April 2018

Figure S3. IDH1 stable knockdown significantly promoted MDA-MB-231 cell motility. (a) The expression...

Additional file 2: of Adipocyte-derived IL-6 and leptin promote breast Cancer metastasis via upregulation of Lysyl Hydroxylase-2 expression

Jin-Yong He (6100892)
Xiao-Hui Wei (6100895)
Si-Jing Li (6100898)
Yang Liu (4829)
Hao-Lin Hu (6100901)
Zheng-Zheng Li (1637104)
Xin-Hong Kuang (6100904)
Lai Wang (23747)
Xin Shi (139139)
Sheng-Tao Yuan (6100907)
Li Sun (4624)

December 2018

Figure S1. Collagen and PLOD2 expression were significantly increased following coculture with adipo...

Additional file 2: of Knockdown delta-5-desaturase in breast cancer cells that overexpress COX-2 results in inhibition of growth, migration and invasion via a dihomo-γ-linolenic acid peroxidation dependent mechanism

Abstract

Extracted data

Additional file 2: of Knockdown delta-5-desaturase in breast cancer cells that overexpress COX-2 results in inhibition of growth, migration and invasion via a dihomo-γ-linolenic acid peroxidation dependent mechanism

Abstract

Extracted data

Related items

Related items