Figure S1. Oligomeric Aβ1–42 specifically binds to TREM2. Figure S2. Oligomeric Aβ1–42 specifically activates TREM2 reporter cells. Figure S3. The number of microglia clustered around Aβ is decreased in Trem2-KO mice. (PDF 1369 kb
Normalized frequency histograms of the α values computed from all the acquired RP-CARS z-stacks in t...
Additional file 6: Figure sup 6. The key molecules that regulate microglialfunctions are up-regulate...
Modifications of brain TREM-2 proteins induced by ARA diet and Aβ42. Immediately after the probe tes...
Figure S2. Expression of TLR2 in microglia. Microglia were prepared and treated as described in the ...
Figure S2. (A) Quantification of amyloid plaque load (% of total ROI area) in male (M) and female (F...
Figure S1. K284-6111and siRNA CHI3L1 on neuroinflammatory and amyloidogenic gene expression and NO g...
The levels of secreted Aβ40 and Aβ42 in BV-2 microglia-conditioned medium. Before added to the prote...
Figure S1–S4. Figure S1 l-leucyl-l-leucine methyl ester (L-LME) depletes enriched astrocytes of micr...
APN deficiency increased the amyloid plaque size and decreased microglia clustering around amyloid d...
Growing evidence suggests that hypertension and aging are prominent risk factors for the development...
Figure S6. Iba1+/TMEM119− cells represent a CD68+ macrophage population with peripheral origin highl...
BV2 microglia in co-culture system exacerbated neuronal loss under AβO exposure. HT-22 cells were tr...
Figure S1. Qualitative immunohistochemical staining for CSF1R receptor (red) in mouse brain cortex s...
Figure S2. Cell counting revealed 95.2% astrocytes and 4.5% microglia. Approximately 0.4% of the cel...
Dot blot analyses using species-specific antibodies. Preparation of Aβ contains both oligomeric and ...
Normalized frequency histograms of the α values computed from all the acquired RP-CARS z-stacks in t...
Additional file 6: Figure sup 6. The key molecules that regulate microglialfunctions are up-regulate...
Modifications of brain TREM-2 proteins induced by ARA diet and Aβ42. Immediately after the probe tes...
Figure S2. Expression of TLR2 in microglia. Microglia were prepared and treated as described in the ...
Figure S2. (A) Quantification of amyloid plaque load (% of total ROI area) in male (M) and female (F...
Figure S1. K284-6111and siRNA CHI3L1 on neuroinflammatory and amyloidogenic gene expression and NO g...
The levels of secreted Aβ40 and Aβ42 in BV-2 microglia-conditioned medium. Before added to the prote...
Figure S1–S4. Figure S1 l-leucyl-l-leucine methyl ester (L-LME) depletes enriched astrocytes of micr...
APN deficiency increased the amyloid plaque size and decreased microglia clustering around amyloid d...
Growing evidence suggests that hypertension and aging are prominent risk factors for the development...
Figure S6. Iba1+/TMEM119− cells represent a CD68+ macrophage population with peripheral origin highl...
BV2 microglia in co-culture system exacerbated neuronal loss under AβO exposure. HT-22 cells were tr...
Figure S1. Qualitative immunohistochemical staining for CSF1R receptor (red) in mouse brain cortex s...
Figure S2. Cell counting revealed 95.2% astrocytes and 4.5% microglia. Approximately 0.4% of the cel...
Dot blot analyses using species-specific antibodies. Preparation of Aβ contains both oligomeric and ...
Normalized frequency histograms of the α values computed from all the acquired RP-CARS z-stacks in t...
Additional file 6: Figure sup 6. The key molecules that regulate microglialfunctions are up-regulate...
Modifications of brain TREM-2 proteins induced by ARA diet and Aβ42. Immediately after the probe tes...