Comparison of the predicted amino acid sequences of 7 HVRs of 25 hexon variants (3Hv-1 to 3Hv-25) of HAdV-3.

<p>The variant strains were compared with the GB strain. Because 3Hv-1 to 3Hv-4 together comprise the majority (80%) of the variants, one representative strain from each country was selected. One reprentative strain from 3Hv-5 to 3Hv-25 was selected. The AA sequences were aligned by Genetyx software (Genetyx Corporation, Tokyo). The hypervariable regions were marked manually following the description by Miksza et al. (1996). The intervening AA sequences between the HVRs were deleted after alignment. The homology of AAs with GB strains is indicated by an asterisk (*) as well as by a green or red shadow, whereas the variations are indicated by an underscore (_).