<p>Exhaustive attractor search of the IGF/Wnt crosstalk model yielded four single state attractors and one three-states attractor. The frequency of occurrence of each attractor is given as percentage below each column. Each block represents an attractor. The nodes are listed on the y-axis. Each rectangle symbolizes the state of a node: red stands for inactive, green for active.</p
Diagram of attractor: (a) model N with α2 = 4.5 and α3 = 7.8. (b) Model C with α2 = 6.4 and α3 = 5.5...
<p>The horizontal and vertical axes represent the values of parameters <i>K</i><sub>34</sub>, <i>K</...
<p>Model 1 is the network as shown in <a href="http://www.plosone.org/article/info:doi/10.1371/journ...
<p>(A) Simulation of the IGF sub-network lead to attractors A, B and C, the first of which could be ...
<p>Gene activity for all genes of the model is presented at distinct network states. A green box ind...
<p>(A) Based on an initial state where all nodes are inactive, a simulation of a signaling cascade w...
<p>IGF and Wnt signaling are simplified and reduced to their most important nodes. Signaling pathway...
<p>(A) The age-related shift from IGF to Wnt happens stepwise. At the beginning of this shift both s...
<p>Attractors and cell types The stationary states of the regulatory network correspond to multiple ...
<p>Each column is associated with a node in the model, each row represents an attractor state (fixed...
<p>Each version of the model illustrated the presence of simple attractors, the complex (loose) attr...
<p>100% of the whole set of network configurations converges to a unique attractor composed by 11 co...
A. Illustration of the network topology searching. Dashed arrows are regulations sampled. The topolo...
Mathematical models of artificial networks can be formulated in terms of dynamical systems describin...
<p>These attractors are divided in four groups: wild-type, broad-stripe, no segmentation and ectopic...
Diagram of attractor: (a) model N with α2 = 4.5 and α3 = 7.8. (b) Model C with α2 = 6.4 and α3 = 5.5...
<p>The horizontal and vertical axes represent the values of parameters <i>K</i><sub>34</sub>, <i>K</...
<p>Model 1 is the network as shown in <a href="http://www.plosone.org/article/info:doi/10.1371/journ...
<p>(A) Simulation of the IGF sub-network lead to attractors A, B and C, the first of which could be ...
<p>Gene activity for all genes of the model is presented at distinct network states. A green box ind...
<p>(A) Based on an initial state where all nodes are inactive, a simulation of a signaling cascade w...
<p>IGF and Wnt signaling are simplified and reduced to their most important nodes. Signaling pathway...
<p>(A) The age-related shift from IGF to Wnt happens stepwise. At the beginning of this shift both s...
<p>Attractors and cell types The stationary states of the regulatory network correspond to multiple ...
<p>Each column is associated with a node in the model, each row represents an attractor state (fixed...
<p>Each version of the model illustrated the presence of simple attractors, the complex (loose) attr...
<p>100% of the whole set of network configurations converges to a unique attractor composed by 11 co...
A. Illustration of the network topology searching. Dashed arrows are regulations sampled. The topolo...
Mathematical models of artificial networks can be formulated in terms of dynamical systems describin...
<p>These attractors are divided in four groups: wild-type, broad-stripe, no segmentation and ectopic...
Diagram of attractor: (a) model N with α2 = 4.5 and α3 = 7.8. (b) Model C with α2 = 6.4 and α3 = 5.5...
<p>The horizontal and vertical axes represent the values of parameters <i>K</i><sub>34</sub>, <i>K</...
<p>Model 1 is the network as shown in <a href="http://www.plosone.org/article/info:doi/10.1371/journ...