IPD incidence in children <5 years and adults >65 years.

<p>PCV7 serotypes include serotypes 4, 6B, 9V, 14, 18C, 19F and 23F. PHiD-CV10 shows the additional serotypes 1, 5 and 7F. PCV13 shows the additional serotypes 3, 6A and 19A. The incidence of IPD was calculated per two epidemiological years. The first bar (June 2004 –June 2006) depicts the IPD incidence in the years before implementation of PCV. The following five bars depict IPD incidence as observed after introduction of pneumococcal vaccination; respectively 1 year after PCV7 implementation (June 2006 –June 2008), 3 years after PCV7 implementation (June 2008 –June 2010), 5 years after PCV7 implementation (June 2010 –June 2012), 2 years after PHiD-CV10 implementation (June 2012 –June 2014) and 4 years after PHiD-CV10 implementation (June 2014 –June 2016).