Figure S5. The activation levels of ALK and STAT3 were inappreciably changed upon H2O2 re-challenge. The expression levels of pALKY1604, ALK, pSTAT3Y705, and STAT3 in RU and RR cells with or without H2O2 re-challenge. The same cell lysates from Fig. 3a were reused in this experiment, and note that the same β-actin blot as the one in Fig. 3a was recycled for H2O2-stimulation in RU and RR cells derived from Karpas 299 cells. (PDF 102 kb
Figure S3. Stemness properties of LGR5+ 8591 cells in vivo. (a) Xenografts produced by LGR5+ and LGR...
Figure S3. Ki67 index is associated with ALDH1A1 expression in mice tumors. Representative images of...
ARHI can induce autophagy in vivo. (a) Immunohistochemistry of SQSTM1, LC3, and Bcl2 in vivo. The sc...
Figure S1. The cell numbers of RU cells derived from SupM2 and Karpas 299 upon various doses of H2O2...
Figure S6. RU cells derived from SupM2 were transfected with either Sox2 siRNA or scrambled siRNA wh...
Figure S2. Anti-oxidant reagent NAC blocked the increase of GFP-positive cells induced by H2O2. A-B)...
NPM-ALK/STAT3 is not differentially activated or expressed between RU and RR cells. (a) The protein ...
Inhibition of MYC by 10074-G5 downregulates the Sox2 downstream target genes in RR cells. (a) SRR2 p...
RU cells transfected with the constitutively active CTNNB1 (CA-CTNNB1) acquire the RR phenotype. (a)...
Abstract Background The phenomenon that malignant cells can acquire stemness under specific stimuli,...
Figure S3. A MDA PA and MDA RES cells were treated with 25 and 50 μM GSK for 48 h. Lactate productio...
PKM2 regulates hypoxia-induced VEGF promoter activity. A, PaTu2 cancer cells were transiently transf...
Characterization of RASV12 transformed MEF expressing (WT RAS MEF) or not (Vdac1 −/− RAS MEF) Vdac1....
Red blood cells are present in Vdac1 −/− RAS MEF tumor tissue. (A) 20 mg of tumor tissue derived fro...
ALDH1A2 expression in HNSCC cell lines and morphological phenotype upon inhibition of ALDH1A2-RAR si...
Figure S3. Stemness properties of LGR5+ 8591 cells in vivo. (a) Xenografts produced by LGR5+ and LGR...
Figure S3. Ki67 index is associated with ALDH1A1 expression in mice tumors. Representative images of...
ARHI can induce autophagy in vivo. (a) Immunohistochemistry of SQSTM1, LC3, and Bcl2 in vivo. The sc...
Figure S1. The cell numbers of RU cells derived from SupM2 and Karpas 299 upon various doses of H2O2...
Figure S6. RU cells derived from SupM2 were transfected with either Sox2 siRNA or scrambled siRNA wh...
Figure S2. Anti-oxidant reagent NAC blocked the increase of GFP-positive cells induced by H2O2. A-B)...
NPM-ALK/STAT3 is not differentially activated or expressed between RU and RR cells. (a) The protein ...
Inhibition of MYC by 10074-G5 downregulates the Sox2 downstream target genes in RR cells. (a) SRR2 p...
RU cells transfected with the constitutively active CTNNB1 (CA-CTNNB1) acquire the RR phenotype. (a)...
Abstract Background The phenomenon that malignant cells can acquire stemness under specific stimuli,...
Figure S3. A MDA PA and MDA RES cells were treated with 25 and 50 μM GSK for 48 h. Lactate productio...
PKM2 regulates hypoxia-induced VEGF promoter activity. A, PaTu2 cancer cells were transiently transf...
Characterization of RASV12 transformed MEF expressing (WT RAS MEF) or not (Vdac1 −/− RAS MEF) Vdac1....
Red blood cells are present in Vdac1 −/− RAS MEF tumor tissue. (A) 20 mg of tumor tissue derived fro...
ALDH1A2 expression in HNSCC cell lines and morphological phenotype upon inhibition of ALDH1A2-RAR si...
Figure S3. Stemness properties of LGR5+ 8591 cells in vivo. (a) Xenografts produced by LGR5+ and LGR...
Figure S3. Ki67 index is associated with ALDH1A1 expression in mice tumors. Representative images of...
ARHI can induce autophagy in vivo. (a) Immunohistochemistry of SQSTM1, LC3, and Bcl2 in vivo. The sc...