Normal density of dendritic spines and expression of synaptic molecules in IP₃K-A Tg mice.

<p>(A), Representative images of Golgi-stained dendritic segments of CA1 and DG neurons in WT and Tg mice. Scale bar, 5 μm. (B), Quantification of dendritic spine density. Mean ± SEM. (WT, n = 60 neurons, 5 mice; Tg, n = 45, 4). (C), Representative images of immunohistochemistry of NR2B (C1), synaptotagmin 1 (SYT1; C2), and PSD-95 (C3) at the apical dendritic region of hippocampal CA1 pyramidal cells. Scale bar, 5 μm. (D), Quantification of immunofluorescent puncta of NR2B, SYT1 and PSD-95.