Synthesis and research on properties of 2-(4-еthyl-5-((3'-methylxantine-7'-yl)methyl)-4H-1,2,4-triazole-3-ylthio)acetic acid’s salts

1,2,4-Triazole derivatives are successfully used in medicine as antibacterial and antifungal agents. Aim of our research is the study of synthesis of 7'-((3-thio-4-ethyl-4H-1,2,4-triazole-5-yl)methyl)-3'-methylxanthine. Methods and results. Sodium salt of 3-methylxanthine has been used as the initial substance to obtain a new series of these compounds. It has been shown that the reaction of the corresponding hydrazide interaction with ethylisothiocyanate finds its continuation in the intramolecular cyclization. The synthesis of 2-(4-ethyl-5-((3'-methylxantine-7'-yl)methyl)-4Н-1,2,4-triazol-3-ylthio)аcetic acid’s salts has been performed. Physical-chemical properties of compounds have been researched and their structure and individuality has been confirmed by elemental analysis, IR-spectroscopy, 1H NMR-spectroscopy, chromato-mass and mass-spectrometry. Conclusion. 12 New compounds have been obtained and their structure has been confirmed