Sphingosine-1-phosphate (S1P) is a low-molecular-weight phospholipid derivative released by activated platelets. S1P transduces signals through a family of G protein-coupled receptors to modulate various physiological behaviors of endothelial cells. Platelet/endothelial cell adhesion molecule-1 (PECAM-1; CD31) is a 130-kDa protein expressed on the surfaces of leukocytes, platelets, and endothelial cells. Upon PECAM-1 activation, its cytoplasmic tyrosine residues become phosphorylated and bind with SH2 domain-containing proteins, thus leading to the downstream functions mediated by PECAM-1. In the present study, we found that S1P induced PECAM-1 tyrosine phosphorylation and SHP-2 association in bovine aortic endothelial cells (BAECs) by immu...
Atherosclerosis is a chronic inflammatory process involving complex interactions of modified lipopro...
[[abstract]]Sphingosine 1-phosphate (S1P), a lysophospholipid mediator, regulates diverse functions ...
Abstract—Sphingosine-1-phosphate (S1P), a multifunctional phospholipid, regulates vascular cell func...
Sphingosine 1-phosphate (S1P) is a multifunctional phospholipid which acts through a specific family...
The sphingosine 1-phosphate receptor 1 (S1P1) is abundant in endothelial cells, where it regulates v...
Sphingosine 1-phosphate (S1P)是一種低分子?的多功能性水解磷酸脂,主要經由被活化的血小板釋放到血液中。S1P 和細胞表面特殊的G 型蛋白耦合受器結合後,會引發下游一??的細...
AbstractPlatelet endothelial cell adhesion molecule-1 (PECAM-1, CD31) is rapidly tyrosine phosphoryl...
Sphingosine I-phosphate (S1P) is stored in and released from platelets in response to cell activatio...
Sphingosine-1-phosphate (S1P), the bioactive product of sphingosine kinase (SK) activation, is a sur...
Sphingosine-1-phosphate (S1P) is a versatile lipid signaling molecule and key regulator in vascular ...
Sphingosine-1-phosphate (S1P), a platelet-derived bioactive lipid, is a potent regulator of angiogen...
Platelet endothelial cell adhesion molecule-1 (PECAM-1/CD31) is a 130-kd transmembrane glycoprotein ...
AbstractRecent studies suggest that sphingosine 1-phosphate (S1P) protects against atherosclerosis. ...
Sphingosine-1-phosphate (S1P) is an agonist for five distinct G-protein coupled receptors, that is r...
Sphingosine-1-phosphate (S1P) is an agonist for five distinct G-protein coupled receptors, that is r...
Atherosclerosis is a chronic inflammatory process involving complex interactions of modified lipopro...
[[abstract]]Sphingosine 1-phosphate (S1P), a lysophospholipid mediator, regulates diverse functions ...
Abstract—Sphingosine-1-phosphate (S1P), a multifunctional phospholipid, regulates vascular cell func...
Sphingosine 1-phosphate (S1P) is a multifunctional phospholipid which acts through a specific family...
The sphingosine 1-phosphate receptor 1 (S1P1) is abundant in endothelial cells, where it regulates v...
Sphingosine 1-phosphate (S1P)是一種低分子?的多功能性水解磷酸脂,主要經由被活化的血小板釋放到血液中。S1P 和細胞表面特殊的G 型蛋白耦合受器結合後,會引發下游一??的細...
AbstractPlatelet endothelial cell adhesion molecule-1 (PECAM-1, CD31) is rapidly tyrosine phosphoryl...
Sphingosine I-phosphate (S1P) is stored in and released from platelets in response to cell activatio...
Sphingosine-1-phosphate (S1P), the bioactive product of sphingosine kinase (SK) activation, is a sur...
Sphingosine-1-phosphate (S1P) is a versatile lipid signaling molecule and key regulator in vascular ...
Sphingosine-1-phosphate (S1P), a platelet-derived bioactive lipid, is a potent regulator of angiogen...
Platelet endothelial cell adhesion molecule-1 (PECAM-1/CD31) is a 130-kd transmembrane glycoprotein ...
AbstractRecent studies suggest that sphingosine 1-phosphate (S1P) protects against atherosclerosis. ...
Sphingosine-1-phosphate (S1P) is an agonist for five distinct G-protein coupled receptors, that is r...
Sphingosine-1-phosphate (S1P) is an agonist for five distinct G-protein coupled receptors, that is r...
Atherosclerosis is a chronic inflammatory process involving complex interactions of modified lipopro...
[[abstract]]Sphingosine 1-phosphate (S1P), a lysophospholipid mediator, regulates diverse functions ...
Abstract—Sphingosine-1-phosphate (S1P), a multifunctional phospholipid, regulates vascular cell func...