The effect of acute caffeine supplementation on C-reactive protein and interleukin-6 responses following super-slow resistance training in trained men

Background and Aims: According to limited and inconsistent results about the effect of acute supplementation of Metyl-Xantine on inflammatory responses following training, this study was to determine the effect of acute caffeine consumption on C-reactive protein and interleukin-6 responses following one session of super-slow resistance training. Material and Method: In order to achieve the purpose of the study, 16 trained males (mean age, 24 ± 0/75 years, and fat percentage 10/3 ± 0/61 and BMI 23 /5 ± 0/49 kg /m2 ) participated in a quasi-experimental design and were randomly assigned in two homogenous groups (n=8): (1) super-slow resistance group with placebo (10 reps, %40 1RM,1 times, total time 120 seconds) and (2) super-slow resistance group with caffeine (6mg/kg). Blood samples were collected before and 24 hours after training to determine C-reactive protein and interleukin-6. Data were analyzed by independent t-test at the significant level (P≤0/05). Findings: The results suggest that super-slow resistance training significantly increased C-reactive protein and IL-6(P≤0/05). The increase in the supplement group was significantly lower. Conclusion: we conclude that super-slow resistance training causes low-grade inflammation increased IL-6 concentrations ( supplement group: from 23/57 to 24/93 pg/ml, placebo group: from 22/48 to 29/08 pg/ml) and C-reactive protein (supplement group: from 0/72 to 0/82 mg/l, placebo group: from 0/69 to 1/2 mg/l ) and acute caffeine consumption can improve inflammatory responses in resistance training male. So we suggest male bodybuilder athletes to acute caffeine supplementation before and during their resistance training session to reduce the inflammatory responses following resistance training