MRF4 is one of four skeletal muscle specific regulatory genes, (the other three genes being MyoD, myf5, and myogenin), each of which has the unique ability to orchestrate an entire program of muscle-specific transcription when introduced into diverse cell types. These findings have led to the notion that these factors function as master regulators of muscle cell fate. Analysis of mice lacking MyoD, myf5, and myogenin have further defined their roles in the commitment and differentiation of myotomal progenitor cells. Current data strongly supports the model that MyoD and myf5 share functional redundancy in determining the muscle cell lineage, while myogenin acts downstream of MyoD and myf5, to initiate myoblast differentiation. Unlike other ...
Skeletal muscle development in the vertebrate embryo critically depends on bHLH myogenic regulatory ...
AbstractGene targeting has indicated that Myf5 and MyoD are required for myogenic determination beca...
Myogenin is a member of the MyoD family of skeletal muscle specific bHLH transcription factors. All ...
MRF4 is one of four skeletal muscle specific regulatory genes, (the other three genes being MyoD, my...
MRF4 (herculin/Myf-6) is one of the four member MyoD family of transcription factors identified by t...
AbstractThe four myogenic basic helix-loop-helix proteins, MyoD, myogenin, Myf-5, and MRF4, can each...
Motivation: The myogenic regulatory factors (MRFs) are a family of basic-helix-loop-helix (bHLH) tra...
AbstractThe myogenic determination genes Myf5, Myod and Mrf4 direct skeletal muscle cell fate prenat...
Myogenesis is studied as an example of vertebrate cell type determination and differentiation mainly...
AbstractThe myogenic determination genes Myf5, Myod and Mrf4 direct skeletal muscle cell fate prenat...
AbstractThe four myogenic basic helix-loop-helix proteins, MyoD, myogenin, Myf-5, and MRF4, can each...
AbstractSkeletal muscle development in the vertebrate embryo critically depends on the myogenic regu...
The muscle-specific transcription factors Myf5 and Mrf4 are two of the four myogenic regulatory fact...
Although mechanisms regulating the formation of embryonic skeletal muscle are well characterized, le...
The final steps of vertebrate skeletal muscle development involve withdrawal of determined muscle pr...
Skeletal muscle development in the vertebrate embryo critically depends on bHLH myogenic regulatory ...
AbstractGene targeting has indicated that Myf5 and MyoD are required for myogenic determination beca...
Myogenin is a member of the MyoD family of skeletal muscle specific bHLH transcription factors. All ...
MRF4 is one of four skeletal muscle specific regulatory genes, (the other three genes being MyoD, my...
MRF4 (herculin/Myf-6) is one of the four member MyoD family of transcription factors identified by t...
AbstractThe four myogenic basic helix-loop-helix proteins, MyoD, myogenin, Myf-5, and MRF4, can each...
Motivation: The myogenic regulatory factors (MRFs) are a family of basic-helix-loop-helix (bHLH) tra...
AbstractThe myogenic determination genes Myf5, Myod and Mrf4 direct skeletal muscle cell fate prenat...
Myogenesis is studied as an example of vertebrate cell type determination and differentiation mainly...
AbstractThe myogenic determination genes Myf5, Myod and Mrf4 direct skeletal muscle cell fate prenat...
AbstractThe four myogenic basic helix-loop-helix proteins, MyoD, myogenin, Myf-5, and MRF4, can each...
AbstractSkeletal muscle development in the vertebrate embryo critically depends on the myogenic regu...
The muscle-specific transcription factors Myf5 and Mrf4 are two of the four myogenic regulatory fact...
Although mechanisms regulating the formation of embryonic skeletal muscle are well characterized, le...
The final steps of vertebrate skeletal muscle development involve withdrawal of determined muscle pr...
Skeletal muscle development in the vertebrate embryo critically depends on bHLH myogenic regulatory ...
AbstractGene targeting has indicated that Myf5 and MyoD are required for myogenic determination beca...
Myogenin is a member of the MyoD family of skeletal muscle specific bHLH transcription factors. All ...