Carcinoma of the cervix is causally related to infection with the human papillomavirus (HPV), and T cells play a pivotal role in the immune response of the host to rid itself of HPV infection. Therefore, we assessed the T-cell function of women with HPV-related cervical neoplasia against a superantigen, Staphylococcus enterotoxin B (SEB). Each woman provided a cervical brush specimen for HPV DNA testing and Papanicolaou (Pap) smears for the staging of cervical lesions. They also provided a blood specimen for determination of the ability of CD4(+) T and CD8(+) T cells to synthesize Th1 (interleukin-2 [IL-2], gamma interferon [IFN-gamma], and tumor necrosis factor alpha [TNF-alpha]) and Th2 (IL-10) cytokines in response to activation with SEB...
Genital papilloma is caused by human papilloma virus (HPV) infection and recurs frequently. Although...
Background: A shifted balance between T helper 1 (Th1)-type and Th2-type cytokines has been hypothes...
This study addressed the notion that the progression of cervical cancer is associated with a T-helpe...
Carcinoma of the cervix is causally related to infection with the human papillomavirus (HPV), and T ...
Background: Genital infection with certain strains of human papillomavirus (HPV) is associated with ...
Background: Genital infection with certain strains of human papillomavirus (HPV) is associated with ...
It has been postulated that an impaired immune response may contribute to the progression of human p...
T-cell-mediated immune responses against oncogenic human papillomaviruses (HPVs) are believed to pla...
Human papillomavirus (HPV) is believed to be the major cause of cervical cancer. To investigate whet...
Cervical cancer is the possible outcome of genital infection with high-risk human papillomavirus (HP...
International audienceOBJECTIVES: Humoral and cellular immune responses are likely to play a key rol...
Cervical neoplastic lesions are associated with infection by high-risk human papilloma viruses (HPVs...
Human papillomaviruses (HPVs) are obligate epithelial pathogens and typically cause localized mucosa...
textabstractAims. We investigated the effect of HR-HPV infection on the capacity of the cytokine net...
Human papillomavirus (HPV) is the causative agent in almost all cervical cancers. Most HPV infection...
Genital papilloma is caused by human papilloma virus (HPV) infection and recurs frequently. Although...
Background: A shifted balance between T helper 1 (Th1)-type and Th2-type cytokines has been hypothes...
This study addressed the notion that the progression of cervical cancer is associated with a T-helpe...
Carcinoma of the cervix is causally related to infection with the human papillomavirus (HPV), and T ...
Background: Genital infection with certain strains of human papillomavirus (HPV) is associated with ...
Background: Genital infection with certain strains of human papillomavirus (HPV) is associated with ...
It has been postulated that an impaired immune response may contribute to the progression of human p...
T-cell-mediated immune responses against oncogenic human papillomaviruses (HPVs) are believed to pla...
Human papillomavirus (HPV) is believed to be the major cause of cervical cancer. To investigate whet...
Cervical cancer is the possible outcome of genital infection with high-risk human papillomavirus (HP...
International audienceOBJECTIVES: Humoral and cellular immune responses are likely to play a key rol...
Cervical neoplastic lesions are associated with infection by high-risk human papilloma viruses (HPVs...
Human papillomaviruses (HPVs) are obligate epithelial pathogens and typically cause localized mucosa...
textabstractAims. We investigated the effect of HR-HPV infection on the capacity of the cytokine net...
Human papillomavirus (HPV) is the causative agent in almost all cervical cancers. Most HPV infection...
Genital papilloma is caused by human papilloma virus (HPV) infection and recurs frequently. Although...
Background: A shifted balance between T helper 1 (Th1)-type and Th2-type cytokines has been hypothes...
This study addressed the notion that the progression of cervical cancer is associated with a T-helpe...