Antimicrobial resistance patterns of pseudomonas aeruginosa in a tertiary care hospital

Objective: To evaluate the antibiotic resistance patterns of Pseudomonas aeruginosa isolated from various clinical samples in a tertiary care hospital. Materials and Methods: Between Mar 2013 to Feb 2014, 386 strains of P. aeruginosa were isolated from different clinical specimens and fully characterized by standard bacteriological procedures. Antimicrobial susceptibility patterns of each isolate were carried out by Kirby- Bauer disk diffusion method and results were interpreted according to Clinical Laboratory Standard Institute guidelines. Results: The isolation rate of P. aeruginosa in this study was 11.5%. Pus,urine and tracheal aspirates were important sources of P. aeruginosa. The highest resistance was reported to Ciprofloxacin while the lowest resistance to Imipenem. 17% of P. aeruginosa isolates were foundto bem ulti - drug resistant (MDR). Conclusion: The clinical significance of thesefindings emphasizes the importance ofjudicious and rational treatment prescription to limit the spread of antimicrobial resistance among P. aeruginosa strains. There is a need for periodical antimicrobial surveillance to monitor the resistance patterns in hospitals and prevent further spread of MDR strains