Autonomous role of Wiskott-Aldrich Syndrome platelet deficiency in inducing autoimmunity and inflammation
- Sereni, Lucia
- Castiello, Maria Carmina
- Marangoni, Francesco
- Anselmo, Achille
- di Silvestre, Dario
- Motta, Sara
- Draghici, Elena
- Mantero, Stefano
- Thrasher, Adrian J
- Giliani, Silvia
- Aiuti, Alessandro
- Mauri, Pierluigi
- Notarangelo, Luigi D
- Bosticardo, Marita
- Villa, Anna
DOIAbstract
Wiskott-Aldrich Syndrome (WAS) is an X-linked immunodeficiency characterized by eczema, infections and susceptibility to develop autoimmunity and malignancies. Thrombocytopenia is a constant finding, but its pathogenesis remains elusive
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