Add to ORKGPreviously, we have developed a single-vessel fMRI method to visualize the hemodynamic signal propagation from individual venules and arterioles in the deep layer cortex and hippocampus. Here, we combined the single-vessel SSFP-fMRI with the GCaMP-mediated calcium recording to decipher the hippocampal neurovascular coupling events. Optogenetic stimulation led to epileptic activity, which could be detected as the bursting calcium spikes coupled to elongated fMRI signal from individual hippocampal arterioles and venules up to 20-30s following the epileptic events. This work establishes a multi-modal fMRI platform to characterize the hippocampal vascular dynamics of both normal and optogenetically driven seizure-like states
In this talk, we will see through the large voxel acquired from conventional fMRI method to decipher...
In the new era of brain research, highlighted by the Human Brain Project and BRAIN Initiative, how t...
The resting-state fMRI signal could be characterized at a single-vessel level to map vascular networ...
Previously, we have developed a single-vessel fMRI method to visualize the hemodynamic signal propag...
Objective: This work is to develop a multi-modal fMRI platform so as to identify the neurovascular c...
Extensive in vivo imaging studies investigate the hippocampal neural network function, mainly focusi...
Optogenetic activation can elicit seizure-like events in the hippocampus of anesthetized rats. Howev...
Previously, we have developed a single-vessel fMRI method to visualize the hemodynamic signal propag...
Functional magnetic resonance imaging (fMRI) could indirectly infer brain activity from the tightly ...
We have developed high resolution single- vessel fMRI to map the hemodynamic signal from individual ...
In this talk, I will introduce the combination of the advanced fMRI method with the emerging neurote...
The neuronal firing patterns across cortical layers have been extensively studied to better depict t...
Neurovascular coupling is the basis of the BOLD fMRI, however, the mechanisms of the neurovascular c...
Introduction Here, we expressed genetically encoded fluorescent reporter iGluSnFR1 for extracellular...
The communication between neurons and blood vessels to supply cells in the brain with energy is a co...
In this talk, we will see through the large voxel acquired from conventional fMRI method to decipher...
In the new era of brain research, highlighted by the Human Brain Project and BRAIN Initiative, how t...
The resting-state fMRI signal could be characterized at a single-vessel level to map vascular networ...
Previously, we have developed a single-vessel fMRI method to visualize the hemodynamic signal propag...
Objective: This work is to develop a multi-modal fMRI platform so as to identify the neurovascular c...
Extensive in vivo imaging studies investigate the hippocampal neural network function, mainly focusi...
Optogenetic activation can elicit seizure-like events in the hippocampus of anesthetized rats. Howev...
Previously, we have developed a single-vessel fMRI method to visualize the hemodynamic signal propag...
Functional magnetic resonance imaging (fMRI) could indirectly infer brain activity from the tightly ...
We have developed high resolution single- vessel fMRI to map the hemodynamic signal from individual ...
In this talk, I will introduce the combination of the advanced fMRI method with the emerging neurote...
The neuronal firing patterns across cortical layers have been extensively studied to better depict t...
Neurovascular coupling is the basis of the BOLD fMRI, however, the mechanisms of the neurovascular c...
Introduction Here, we expressed genetically encoded fluorescent reporter iGluSnFR1 for extracellular...
The communication between neurons and blood vessels to supply cells in the brain with energy is a co...
In this talk, we will see through the large voxel acquired from conventional fMRI method to decipher...
In the new era of brain research, highlighted by the Human Brain Project and BRAIN Initiative, how t...
The resting-state fMRI signal could be characterized at a single-vessel level to map vascular networ...