Topographic distribution of cerebral infarct probability in patients with acute ischemic stroke: mapping of intra-arterial treatment effect
- Boers, A. M. M.
- Berkhemer, O. A.
- Slump, C. H.
- van Zwam, W. H.
- Roos, Y. B. W. E. M.
- van der Lugt, A.
- van Oostenbrugge, R. J.
- Yoo, A. J.
- Dippel, D. W. J.
- Marquering, H. A.
- Majoie, C. B. L. M.
- Fransen, P. S. S.
- Beumer, D.
- van den Berg, L. A.
- Schonewille, W. J.
- Vos, J. A.
- Nederkoorn, P. J.
- Wermer, M. J. H.
- van Walderveen, M. A. A.
- Staals, J.
- Hofmeijer, J.
- van Oostayen, J. A.
- Lycklama à Nijeholt, G. J.
- Boiten, J.
- Brouwer, P. A.
- Emmer, B. J.
- de Bruijn, S. F.
- van Dijk, L. C.
- JKappelle, L.
- Lo, R. H.
- van Dijk, E. J.
- de Vries, J.
- de Kort, P. L. M.
- van den Berg, J. S. P.
- van Hasselt, B. A. A. M.
- Aerden, L. A. M.
- Dallinga, R. J.
- Visser, M. C.
- Bot, J. C. J.
- Vroomen, P. C.
- Eshghi, O.
- Schreuder, Th. C. M. L.
- Heijboer, R. J. J.
- Keizer, K.
- Tielbeek, A. V.
- den Hertog, H. M.
- Beenen, L. F.
- Sprengers, M. E. S.
- van den Berg, R.
- Fleitour, Nadine
DOIAbstract
Background Since proof emerged that IA treatment (IAT) is beneficial for patients with acute ischemic stroke, it has become the standard method of care. Despite these positive results, recovery to functional independence is established in only about one-third of treated patients. The effect of IAT is commonly assessed by functional outcome, whereas its effect on brain tissue salvage is considered a secondary outcome measure (at most). Because patient and treatment selection needs to be improved, understanding the treatment effect on brain tissue salvage is of utmost importance. Objective To introduce infarct probability maps to estimate the location and extent of tissue damage based on patient baseline characteristics and treatment type. Me...
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