Cells were incubated with vehicle, ., non-stimulated, or increasing concentration of gefitinib for 24, 48, and 72 hours. Comparison of cellular growth in response to gefitinib (3.75 μM), EGF (100 ng/ml) and vehicle ., non-stimulated. The represent SD of results of separate wells. * p < 0.05, versus similar dosage in parental ACCS cells at 24 and 48 hrs. ** p < 0.05, versus similar dosage in ACCS cells at 24 and 48 hrs.<p><b>Copyright information:</b></p><p>Taken from "Tyrosine-kinase inhibition results in EGFR clustering at focal adhesions and consequent exocytosis in uPAR down-regulated cells of Head and Neck cancers"</p><p>http://www.molecular-cancer.com/content/7/1/47</p><p>Molecular Cancer 2008;7():47-47.</p><p>Published online 3 Jun 20...
<p>(<b>A</b>) OSC19 cells were treated with the indicated concentrations of erlotinib, a small molec...
<p>(<b>A</b>) MCF7-GFPLC3 cells treated for 3 h with vehicle (0 µM gefitinib) or indicated doses of ...
<p>A. RT-qPCR evaluation of the basal total EGFR mRNA expression in MCF-7, TAM-R and TAM-Wd cells. D...
Total EGFR and total ERK are also shown for comparison. β-actin western blots and Coomassie blue sta...
<p>The effects of (A) gefitinib and (B) erlotinib (1–10 μM) on cell proliferation of A549 cells were...
<p><b>Copyright information:</b></p><p>Taken from "Responses of cancer cells with wild-type or tyros...
<p>Time course of 10 nM [<sup>3</sup>H]gefitinib (A) and 1 μM Hoechst 33342 (B) accumulation in H460...
<p>(A) Parental HCC78 and HCC78-TR cells were treated with gefitinib as a single-agent for 3 days an...
There was also vacuolar formation observed as early as 10 minutes in ACCS-AS cell lines which contin...
<p>(A) MTS assay comparing the survival curves of control JLO-1 to 2 µM gefitinib-treated JLO-1 when...
<p><b>Copyright information:</b></p><p>Taken from "Responses of cancer cells with wild-type or tyros...
<p>RNA and protein was isolated from UMSCC25, 584-A2, and Ca9-22 HNSCC cell lines that were treated ...
<p><b>A.</b> Cells were cultured in the presence (+ EGF) or absence (- EGF) of EGF and their prolife...
<p>The three indicated NSCLC cell lines, H3255 (L858R mutation), H1975 (both T790M and L858R mutatio...
<p>(A) EGF increased the rate of sphere formation in a dose-dependent fashion in 22B and HN-1 cells,...
<p>(<b>A</b>) OSC19 cells were treated with the indicated concentrations of erlotinib, a small molec...
<p>(<b>A</b>) MCF7-GFPLC3 cells treated for 3 h with vehicle (0 µM gefitinib) or indicated doses of ...
<p>A. RT-qPCR evaluation of the basal total EGFR mRNA expression in MCF-7, TAM-R and TAM-Wd cells. D...
Total EGFR and total ERK are also shown for comparison. β-actin western blots and Coomassie blue sta...
<p>The effects of (A) gefitinib and (B) erlotinib (1–10 μM) on cell proliferation of A549 cells were...
<p><b>Copyright information:</b></p><p>Taken from "Responses of cancer cells with wild-type or tyros...
<p>Time course of 10 nM [<sup>3</sup>H]gefitinib (A) and 1 μM Hoechst 33342 (B) accumulation in H460...
<p>(A) Parental HCC78 and HCC78-TR cells were treated with gefitinib as a single-agent for 3 days an...
There was also vacuolar formation observed as early as 10 minutes in ACCS-AS cell lines which contin...
<p>(A) MTS assay comparing the survival curves of control JLO-1 to 2 µM gefitinib-treated JLO-1 when...
<p><b>Copyright information:</b></p><p>Taken from "Responses of cancer cells with wild-type or tyros...
<p>RNA and protein was isolated from UMSCC25, 584-A2, and Ca9-22 HNSCC cell lines that were treated ...
<p><b>A.</b> Cells were cultured in the presence (+ EGF) or absence (- EGF) of EGF and their prolife...
<p>The three indicated NSCLC cell lines, H3255 (L858R mutation), H1975 (both T790M and L858R mutatio...
<p>(A) EGF increased the rate of sphere formation in a dose-dependent fashion in 22B and HN-1 cells,...
<p>(<b>A</b>) OSC19 cells were treated with the indicated concentrations of erlotinib, a small molec...
<p>(<b>A</b>) MCF7-GFPLC3 cells treated for 3 h with vehicle (0 µM gefitinib) or indicated doses of ...
<p>A. RT-qPCR evaluation of the basal total EGFR mRNA expression in MCF-7, TAM-R and TAM-Wd cells. D...