After 48 h of incubation IFNγ dose-dependently induced an arrest in the S-phase of the cell cycle of BON cells

<p><b>Copyright information:</b></p><p>Taken from "A novel approach in the treatment of neuroendocrine gastrointestinal tumors: Additive antiproliferative effects of interferon-γ and meta-iodobenzylguanidine"</p><p>BMC Cancer 2004;4():23-23.</p><p>Published online 21 May 2004</p><p>PMCID:PMC442128.</p><p>Copyright © 2004 Höpfner et al; licensee BioMed Central Ltd. This is an Open Access article: verbatim copying and redistribution of this article are permitted in all media for any purpose, provided this notice is preserved along with the article's original URL.</p> Accordingly, the proportion of cells in the G/M-phase decreased. Differences in the proportion of cells in the respective phase of cell cycle versus control were significant from 250 to 500 U/ml IFNγ (p < 0.05). Incubation of BON cells with MIBG for 48 h induced a dose-dependent arrest in the G/G-phase, while the proportion of cells in the G/M-phase decreased. Differences in the proportion of cells in the respective phase of cell cycle versus control were significant at 10 and 50 μM MIBG (