<p><b>Copyright information:</b></p><p>Taken from "A novel DNA damage recognition protein in "</p><p>Nucleic Acids Research 2006;34(8):2347-2354.</p><p>Published online 5 May 2006</p><p>PMCID:PMC1458281.</p><p>© The Author 2006. Published by Oxford University Press. All rights reserved</p> () Effect of heat on ATL activity (triangles, Atl1; squares, eATL; continuous line, before heating; broken line, after heating; open circle, MGMT activity after heating). () Effect of preincubation with Atl1 on the ability of oligonucleotides containing -benzylguanine (filled diamonds) or -(4-bromothenyl)guanine (open diamonds) to inactivate MGMT. Inhibition of MGMT by Atl1is indicated by open triangles
Click here to view linked References Abstract 18 O 6 meG is one of the most pre-mutagenic, pre-carci...
O6-methylguanine-DNA methyltransferase (MGMT) is one of the major DNA repair protein that counteract...
The nucleotide analogue azacitidine (AZA) is currently the best treatment option for patients with h...
Toxic and mutagenic O6-alkylguanine adducts in DNA are repaired by O6-alkylguanine-DNA alkyltrans-fe...
The DNA mismatch repair (MMR) system maintains genome integrity by correcting replication errors. MM...
High mobility group A, HMGA, proteins are architectural proteins that bind to the minor groove of AT...
The methyl-directed mismatch repair (MMR) mechanism has been extensively studied in vitro and in viv...
ATR is an essential protein that functions as a damage sensor and a proximal kinase in the DNA damag...
The methyl-directed mismatch repair (MMR) mechanism has been extensively studied in vitro and in viv...
<p><b>Copyright information:</b></p><p>Taken from "Recognition and binding of mismatch repair protei...
<p><b>Copyright information:</b></p><p>Taken from "Identification of putative transcriptional regula...
In Escherichia coli, MutS initiates mismatch repair (MMR) by binding mispaired DNA. MutL, an interme...
Proper DNA damage repair is essential for maintaining genomic integrity and stability of all living ...
International audienceIn both pro-and eukaryotes, the mutagenic and toxic DNA adduct O 6-methylguani...
Each of us begins life as a single cell containing our DNA and a complement of varied pieces of mach...
Click here to view linked References Abstract 18 O 6 meG is one of the most pre-mutagenic, pre-carci...
O6-methylguanine-DNA methyltransferase (MGMT) is one of the major DNA repair protein that counteract...
The nucleotide analogue azacitidine (AZA) is currently the best treatment option for patients with h...
Toxic and mutagenic O6-alkylguanine adducts in DNA are repaired by O6-alkylguanine-DNA alkyltrans-fe...
The DNA mismatch repair (MMR) system maintains genome integrity by correcting replication errors. MM...
High mobility group A, HMGA, proteins are architectural proteins that bind to the minor groove of AT...
The methyl-directed mismatch repair (MMR) mechanism has been extensively studied in vitro and in viv...
ATR is an essential protein that functions as a damage sensor and a proximal kinase in the DNA damag...
The methyl-directed mismatch repair (MMR) mechanism has been extensively studied in vitro and in viv...
<p><b>Copyright information:</b></p><p>Taken from "Recognition and binding of mismatch repair protei...
<p><b>Copyright information:</b></p><p>Taken from "Identification of putative transcriptional regula...
In Escherichia coli, MutS initiates mismatch repair (MMR) by binding mispaired DNA. MutL, an interme...
Proper DNA damage repair is essential for maintaining genomic integrity and stability of all living ...
International audienceIn both pro-and eukaryotes, the mutagenic and toxic DNA adduct O 6-methylguani...
Each of us begins life as a single cell containing our DNA and a complement of varied pieces of mach...
Click here to view linked References Abstract 18 O 6 meG is one of the most pre-mutagenic, pre-carci...
O6-methylguanine-DNA methyltransferase (MGMT) is one of the major DNA repair protein that counteract...
The nucleotide analogue azacitidine (AZA) is currently the best treatment option for patients with h...