Requirement of aggregation propensity of Alzheimer amyloid peptides for neuronal cell surface binding-5

<p><b>Copyright information:</b></p><p>Taken from "Requirement of aggregation propensity of Alzheimer amyloid peptides for neuronal cell surface binding"</p><p>http://www.biomedcentral.com/1471-2202/8/29</p><p>BMC Neuroscience 2007;8():29-29.</p><p>Published online 2 May 2007</p><p>PMCID:PMC1871596.</p><p></p>GF differentiated PC12 cells, while treatments that target cell surface lipids or carbohydrates had no effect. SBTI-inactivated trypsin had little effect on Aβ42 association. (B) Concentration dependence of trypsin treated NGF differentiated PC12 cells with 0, 5, 10 and 100 μg/mL trypsin as indicated, followed by 1 hour Aβ42 treatment. (C) 10 μg/mL trypsin treatment of NGF differentiated PC12 cells demonstrate that Aβ42 association with the cell surface recovers over time