Dorsal (,) and frontal (,) view of newly metamorphosed (Gosner stage 46) control (,) and similar-aged animal exposed to the nine-pesticide mixture (,)

<p><b>Copyright information:</b></p><p>Taken from "Pesticide Mixtures, Endocrine Disruption, and Amphibian Declines: Are We Underestimating the Impact?"</p><p></p><p>Environmental Health Perspectives 2006;114(S-1):40-50.</p><p>Published online 24 Jan 2006</p><p>PMCID:PMC1874187.</p><p>This is an Open Access article: verbatim copying and redistribution of this article are permitted in all media for any purpose, provided this notice is preserved along with the article's original DOI</p> Control animal is in good body condition as expected. The pesticide-treated animal is in poor body condition because of a generalized gram-negative bacterial infection. The pathogen was identified in control and treated frogs, but only pesticide-exposed animals show signs of disease: head tilt, unilateral extensor muscle rigidity, anisocoria, and intermittent recumbency due to a severe otitis interna and meningitis. This presentation is consistent with infection, a stress-induced disease of frogs